The formation of new blood vessels, called angiogenesis, is an essential pathophysiological
process in which several families of regulators have been implicated. Among these, vascular …

The simultaneous maturation of multiple digital and telecommunications technologies in
2020 has created an unprecedented opportunity for ophthalmology to adapt to new models …

INTRODUCTION Vision provides a critical survival advantage but requires a tight coupling
between neuronal energy demands and their vascular supply. The degeneration and …

The progressive increase in lifespan over the past century carries with it some adversity
related to the accompanying burden of debilitating diseases prevalent in the older …

Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from
a binding site with unknown function to a firmly established major effector within the …

Importance There are potential benefits and harms of hyperoxemia and hypoxemia for
extremely preterm infants receiving more vs less supplemental oxygen. Objective To …

Attenuating pathological angiogenesis in diseases characterized by neovascularization
such as diabetic retinopathy has transformed standards of care. Yet little is known about the …

The mammalian visual system encodes information over a remarkable breadth of
spatiotemporal scales and light intensities. This performance originates with its complement …

Oxidative stress occurs through an imbalance between the generation of reactive oxygen
species (ROS) and the antioxidant defense mechanisms of cells. The eye is particularly …

Retinopathy of prematurity (ROP) affects only premature infants, but as premature births
increase in many areas of the world, ROP has become a leading cause of childhood …