Hookworms are soil-transmitted nematode parasites that can reside for many years in the
small intestine of their human hosts; Necator americanus is the predominant infecting …

European grassland‐based livestock production systems face the challenge of producing
more meat and milk to meet increasing world demands and to achieve this using fewer …

Intestinal helminths are potent regulators of their host's immune system and can ameliorate
inflammatory diseases such as allergic asthma. In the present study we have assessed …

In vertebrates, activation of innate immunity is an early response to injury, implicating it in the
regenerative process. However, the mechanisms by which innate signals might regulate …

Metabolism and immunity are two fundamental systems of metazoans. The presence of
immune cells, such as macrophages, in metabolic tissues suggests dynamic, ongoing …

Toll-like receptors (TLRs) are recognition molecules for multiple pathogens, including
bacteria, viruses, fungi, and parasites. TLR2 forms heterodimers with TLR1 and TLR6, which …

Extracellular vesicles (EVs) have emerged as a ubiquitous mechanism for transferring
information between cells and organisms across all three kingdoms of life. In addition to their …

Helminth parasites infect almost one-third of the world's population, primarily in tropical
regions. However, regions where helminth parasites are endemic record much lower …

The vertebrate immune system has evolved in concert with a broad range of infectious
agents, including ubiquitous helminth (worm) parasites. The constant pressure of helminth …

Helminths have evolved to become experts at subverting immune surveillance. Through
potent and persistent immune tempering, helminths can remain undetected in human …