Inflammation and preterm birth

M Cappelletti, S Della Bella, E Ferrazzi… - Journal of Leucocyte …, 2016 - academic.oup.com
Preterm birth is the leading cause of neonatal morbidity and mortality. Although the
underlying causes of pregnancy-associated complication are numerous, it is well …

[HTML][HTML] Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National …

JV Ilekis, E Tsilou, S Fisher, VM Abrahams… - American journal of …, 2016 - Elsevier
Although much progress is being made in understanding the molecular pathways in the
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …

Amniotic fluid infection, inflammation, and colonization in preterm labor with intact membranes

CA Combs, M Gravett, TJ Garite, DE Hickok… - American journal of …, 2014 - Elsevier
Objective The purpose of this study was to compare intraamniotic inflammation vs microbial
invasion of the amniotic cavity (MIAC) as predictors of adverse outcome in preterm labor with …

Intrauterine infection and preterm labor

V Agrawal, E Hirsch - Seminars in Fetal and Neonatal Medicine, 2012 - Elsevier
Preterm labor is defined as labor that begins before 37 completed weeks of pregnancy.
More than 12% of infants born in the USA are preterm. At least 40% of preterm births are …

Cervical remodeling during pregnancy and parturition

B Timmons, M Akins, M Mahendroo - Trends in Endocrinology & …, 2010 - cell.com
Appropriate and timely cervical remodeling is key for successful birth. Premature cervical
opening can result in preterm birth which occurs in 12.5% of pregnancies. Research focused …

Toll‐like receptors at the maternal–fetal interface in normal pregnancy and pregnancy disorders

K Koga, G Mor - American journal of reproductive immunology, 2010 - Wiley Online Library
Citation Koga K, Mor G. Toll‐like receptors at the maternal–fetal interface in normal
pregnancy and pregnancy disorders. Am J Reprod Immunol 2010 Toll‐like receptors (TLR) …

Intrauterine infection, immune system and premature birth

FR Helmo, EAR Alves, RAA Moreira… - The journal of …, 2018 - Taylor & Francis
Preterm birth accounts for nearly one million deaths among children under five years of age,
and although its etiopathogenesis is not fully elucidated, ascending intrauterine infection …

Uterine overdistention induces preterm labor mediated by inflammation: observations in pregnant women and nonhuman primates

KMA Waldorf, N Singh, AR Mohan, RC Young… - American journal of …, 2015 - Elsevier
Objective Uterine overdistention is thought to induce preterm labor in women with twin and
multiple pregnancies, but the pathophysiology remains unclear. We investigated for the first …

Are animal models relevant to key aspects of human parturition?

BF Mitchell, MJ Taggart - American Journal of Physiology …, 2009 - journals.physiology.org
Preterm birth remains the most serious complication of pregnancy and is associated with
increased rates of infant death or permanent neurodevelopmental disability. Our …

Ureaplasma parvum or Mycoplasma hominis as Sole Pathogens Cause Chorioamnionitis, Preterm Delivery, and Fetal Pneumonia in Rhesus Macaques

MJ Novy, L Duffy, MK Axthelm, DW Sadowsky… - Reproductive …, 2009 - Springer
The authors assess causal, cellular and inflammatory links between intraamniotic infection
with Ureaplasma parvum or Mycoplasma hominis and preterm labor in a nonhuman primate …