Physiology of astroglia
A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
Incomplete response to Anti-VEGF therapy in neovascular AMD: Exploring disease mechanisms and therapeutic opportunities
PS Mettu, MJ Allingham, SW Cousins - Progress in retinal and eye …, 2021 - Elsevier
Intravitreal anti-vascular endothelial growth factor (VEGF) drugs have revolutionized the
treatment of neovascular age-related macular degeneration (NVAMD). However, many …
treatment of neovascular age-related macular degeneration (NVAMD). However, many …
Glia of the human retina
A Reichenbach, A Bringmann - Glia, 2020 - Wiley Online Library
The human retina contains three types of glial cells: microglia and two types of macroglia,
astrocytes and Müller cells. Macroglia provide homeostatic and metabolic support to …
astrocytes and Müller cells. Macroglia provide homeostatic and metabolic support to …
[HTML][HTML] Glia–neuron interactions in the mammalian retina
The mammalian retina provides an excellent opportunity to study glia–neuron interactions
and the interactions of glia with blood vessels. Three main types of glial cells are found in …
and the interactions of glia with blood vessels. Three main types of glial cells are found in …
New functions of Müller cells
A Reichenbach, A Bringmann - Glia, 2013 - Wiley Online Library
Müller cells, the major type of glial cells in the retina, are responsible for the homeostatic and
metabolic support of retinal neurons. By mediating transcellular ion, water, and bicarbonate …
metabolic support of retinal neurons. By mediating transcellular ion, water, and bicarbonate …
Astrocyte regulation of blood flow in the brain
BA MacVicar, EA Newman - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Neuronal activity results in increased blood flow in the brain, a response named functional
hyperemia. Astrocytes play an important role in mediating this response. Neurotransmitters …
hyperemia. Astrocytes play an important role in mediating this response. Neurotransmitters …
Inwardly rectifying potassium channels: their structure, function, and physiological roles
H Hibino, A Inanobe, K Furutani… - Physiological …, 2010 - journals.physiology.org
Inwardly rectifying K+ (Kir) channels allow K+ to move more easily into rather than out of the
cell. They have diverse physiological functions depending on their type and their location …
cell. They have diverse physiological functions depending on their type and their location …
Cellular and physiological mechanisms underlying blood flow regulation in the retina and choroid in health and disease
J Kur, EA Newman, T Chan-Ling - Progress in retinal and eye research, 2012 - Elsevier
We review the cellular and physiological mechanisms responsible for the regulation of blood
flow in the retina and choroid in health and disease. Due to the intrinsic light sensitivity of the …
flow in the retina and choroid in health and disease. Due to the intrinsic light sensitivity of the …
Heterogeneity of astrocytic form and function
NA Oberheim, SA Goldman, M Nedergaard - Astrocytes: Methods and …, 2012 - Springer
Astrocytes participate in all essential CNS functions, including blood flow regulation, energy
metabolism, ion and water homeostasis, immune defence, neurotransmission, and adult …
metabolism, ion and water homeostasis, immune defence, neurotransmission, and adult …
Physiological roles of aquaporin-4 in brain
EA Nagelhus, OP Ottersen - Physiological reviews, 2013 - journals.physiology.org
Aquaporin-4 (AQP4) is one of the most abundant molecules in the brain and is particularly
prevalent in astrocytic membranes at the blood-brain and brain-liquor interfaces. While …
prevalent in astrocytic membranes at the blood-brain and brain-liquor interfaces. While …