The multifaceted benefits of walking for healthy aging: From Blue Zones to molecular mechanisms

Z Ungvari, V Fazekas-Pongor, A Csiszar, SK Kunutsor - Geroscience, 2023 - Springer
Physical activity, including walking, has numerous health benefits in older adults, supported
by a plethora of observational and interventional studies. Walking decreases the risk or …

Plasma versus serum for extracellular vesicle (EV) isolation: A duel for reproducibility and accuracy for CNS‐originating EVs biomarker analysis

HB Taha - Journal of Neuroscience Research, 2023 - Wiley Online Library
Blood‐derived extracellular vesicles (EVs) are a popular source of biomarkers for central
nervous system (CNS) diseases, but inconsistencies in isolation and analysis hinder their …

Resistance exercise differentially alters extracellular vesicle size and subpopulation characteristics in healthy men and women: An observational cohort study

WR Conkright, ME Beckner… - Physiological …, 2022 - journals.physiology.org
Extracellular vesicles (EVs) are established mediators of adaptation to exercise. Currently,
there are no published data comparing changes in EVs between men and women after …

Running from stress: a perspective on the potential benefits of exercise-induced small extracellular vesicles for individuals with major depressive disorder

R Khoury, C Nagy - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Aerobic exercise promotes beneficial effects in the brain including increased synaptic
plasticity and neurogenesis and regulates neuroinflammation and stress response via the …

Extracellular Vesicles for Alzheimer Disease and Dementia Diagnosis

HB Taha - medRxiv, 2024 - medrxiv.org
Accurate differential diagnosis of dementia disorders including Alzheimer disease (AD),
frontotemporal dementia (FTD), dementia with Lewy bodies (DLB), Parkinson disease …

[HTML][HTML] Exploring the Impact of Exercise-Derived Extracellular Vesicles in Cancer Biology

M Silvestri, E Grazioli, G Duranti, P Sgrò, I Dimauro - Biology, 2024 - mdpi.com
Simple Summary Cancer continues to be a major medical challenge, highlighting the need
for new treatment strategies. One promising area of research is the role of exercise-derived …

The association between the size of adipocyte-derived extracellular vesicles and fasting serum triglyceride-glucose index as proxy measures of adipose tissue insulin …

J Delgadillo-Velázquez, E Alday… - Frontiers in …, 2024 - frontiersin.org
Introduction Obesity is a complex disease that predisposes individuals to cardiometabolic
alterations. It leads to adipose tissue (AT) dysfunction, which triggers insulin resistance (IR) …

Extracellular vesicles as standard-of-care therapy: will fast-tracking the regulatory processes help achieve the goal?

V Kale - Regenerative Medicine, 2024 - Taylor & Francis
ABSTRACT Extracellular Vesicles (EVs) became a focus of clinical research when
experimental and pre-clinical studies showed that they mimic their parent cells' regenerative …

Chronic contractile activity induced skeletal muscle-derived extracellular vesicles increase mitochondrial biogenesis in recipient myocytes via transmembrane or …

PO Obi, TFG Souza, S Seif, B Bydak, N Klassen… - bioRxiv, 2024 - biorxiv.org
The effect of chronic contractile activity (CCA) on the biophysical properties and functional
activity of skeletal muscle extracellular vesicles (Skm-EVs) is poorly understood due to …

Effects of the DailyColors™ Polyphenol Supplement on Serum Proteome, Cognitive Function, and Health in Older Adults at Risk of Cognitive and Functional Decline.

M O'Leary, JL Bowtell, M Richards, E Bozbas, A Palmer… - medRxiv, 2024 - medrxiv.org
The Mediterranean diet is associated with reduced mortality and cognitive decline, largely
due to its polyphenol content. However, Western populations often do not meet …