Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies

K Ulbrich, K Hola, V Subr, A Bakandritsos… - Chemical …, 2016 - ACS Publications
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …

Cancer drug delivery in the nano era: An overview and perspectives

Z Li, S Tan, S Li, Q Shen, K Wang - Oncology reports, 2017 - spandidos-publications.com
Nanomaterials are increasingly used as drug carriers for cancer therapy. Nanomaterials
also appeal to researchers in the areas of cancer diagnosis and biomarker discovery …

The interplay between PEGylated nanoparticles and blood immune system

C Guo, H Yuan, Y Wang, Y Feng, Y Zhang, T Yin… - Advanced Drug Delivery …, 2023 - Elsevier
During the last two decades, an increasing number of reports have pointed out that the
immunogenicity of polyethylene glycol (PEG) may trigger accelerated blood clearance …

Sustained drug release from smart nanoparticles in cancer therapy: a comprehensive review

X Bai, ZL Smith, Y Wang, S Butterworth, A Tirella - Micromachines, 2022 - mdpi.com
Although nanomedicine has been highly investigated for cancer treatment over the past
decades, only a few nanomedicines are currently approved and in the market; making this …

Recent insights in nanotechnology-based drugs and formulations designed for effective anti-cancer therapy

E Piktel, K Niemirowicz, M Wątek, T Wollny… - Journal of …, 2016 - Springer
The rapid development of nanotechnology provides alternative approaches to overcome
several limitations of conventional anti-cancer therapy. Drug targeting using functionalized …

Progress in polymeric nano-medicines for theranostic cancer treatment

I Ali, M Alsehli, L Scotti, M Tullius Scotti, ST Tsai, RS Yu… - Polymers, 2020 - mdpi.com
Cancer is a life-threatening disease killing millions of people globally. Among various
medical treatments, nano-medicines are gaining importance continuously. Many …

Drug delivery in cancer therapy, quo vadis?

ZR Lu, P Qiao - Molecular Pharmaceutics, 2018 - ACS Publications
The treatment of malignancies has undergone dramatic changes in the past few decades.
Advances in drug delivery techniques and nanotechnology have allowed for new …

A ROS-responsive aspirin polymeric prodrug for modulation of tumor microenvironment and cancer immunotherapy

S Ma, W Song, Y Xu, X Si, Y Zhang, Z Tang… - CCS …, 2020 - chinesechemsoc.org
Tumor-promoting inflammation is accompanied by cancer initiation, progression, and
metastasis. Cyclooxygenase-2 (COX-2) and its downstream product, prostaglandin E2 …

Nanomedicine-based intraperitoneal therapy for the treatment of peritoneal carcinomatosis—Mission possible?

GR Dakwar, M Shariati, W Willaert, W Ceelen… - Advanced drug delivery …, 2017 - Elsevier
Intraperitoneal (IP) drug delivery represents an attractive strategy for the local treatment of
peritoneal carcinomatosis (PC). Over the past decade, a lot of effort has been put both in the …

Magnetically assisted intraperitoneal drug delivery for cancer chemotherapy

M Shamsi, A Sedaghatkish, M Dejam, M Saghafian… - Drug …, 2018 - Taylor & Francis
Intraperitoneal (IP) chemotherapy has revived hopes during the past few years for the
management of peritoneal disseminations of digestive and gynecological cancers …