In this review we compare and discuss results of compounds already reported as anticancer
agents based on isatin-derivatives, metalated as well as non-metallated. Isatin compounds …

Schiff bases are a diverse group of organic compounds with great pharmaceutical
importance due to the presence of carbon–nitrogen double bonds (–C= N–). These …

Isatin is an important compound from the biological aspect of view. It is an endogenous
substance and moreover; various pharmacological activities have been reported for isatin …

This review focuses on the potential of indolin-2-one in the treatment of cancer as a
chemotherapeutic nucleus and highlights significant recent progress in the synthetic …

The isatin-core in compounds offers exciting perspectives in medicinal and pharmacological
research. The present study reports the successful development of new isatin-core transition …

Novel hydroxyl-substituted double Schiff-base 4-piperidone/cyclohexanone derivatives, 3a–
e, 4a–e, 5a–d, and 6a–c, were synthesized and fully characterized by 1H NMR, IR and …

A series of new 1H-benzo [d] imidazole derivatives of dehydroabietic acid were designed
and synthesized as potent antitumor agents. Structures of the target molecules were …

Herein, we report the synthesis, characterization, and biological properties of eleven (3a-3k)
novel Schiff bases. The spectral data of FT-IR, 1 H NMR, 13 C NMR, and LC-MS are …

The condensation of N-propyl isatin (1) with different carboxylic acid hydrazides
(RCONHNH2 (2–6), R= arene) via sonication was used to synthesize five new hydrazones …

Several isatin-3-thiosemicarbazones (a class of Schiff bases) from our earlier studies have
been validated as promising cytotoxic agents and urease inhibitors. Also, a number of isatin …