Over the past two decades, bile acids (BAs) have become established as important
signaling molecules that enable fine-tuned inter-tissue communication from the liver, their …

Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all
aspects of organismal biology. Caenorhabditis elegans eat bacteria, which consist of lipids …

Caenorhabditis elegans survives on ephemeral food sources in the wild, and the species
has a variety of adaptive responses to starvation. These features of its life history make the …

Steroid hormones are responsible for the coordinated regulation of many aspects of
biological processes in multicellular organisms. Since the last century, many studies have …

Covering: up to December 2014 Chemical ecology elucidates the nature and role of natural
products as mediators of organismal interactions. The emerging techniques that can be …

Citrus fruit has long been considered a healthy food, but its role and detailed mechanism in
lifespan extension are not clear. Here, by using the nematode C. elegans, we identified that …

Omics tools provide broad datasets for biological discovery. However, the computational
tools for identifying important genes or pathways in RNA-seq, proteomics, or GWAS …

Key discoveries in aging research have been made possible with the use of model
organisms. Caenorhabditis elegans is a short-lived nematode that has become a well …

Specific bile acids and their signaling pathways play important roles in control of
(cholesterol) metabolism. Deeper insight into the interactions between endogenous (ie, bile …

Over the past decade, studies conducted in Caenorhabditis elegans have helped to uncover
the ancient and complex origins of body fat regulation. This review highlights the powerful …