Antigenic variation as a strategy to evade the host adaptive immune response has evolved
in divergent pathogens. Antigenic variation involves restricted, and often mutually exclusive …

Apicomplexan parasites are protozoan organisms that are characterised by complex life
cycles and they include medically important species, such as the malaria parasite …

Transcriptional enhancers direct precise gene expression patterns during development and
harbor the majority of variants associated with phenotypic diversity, evolutionary …

During its asexual blood stage, P. falciparum replicates via schizogony, wherein dozens of
daughter cells are formed within a single parent. The basal complex, a contractile ring that …

Malaria parasites have a complex life cycle featuring diverse developmental strategies, each
uniquely adapted to navigate specific host environments. Here we use single-cell …

Plasmodium falciparum secretes extracellular vesicles (Pf EVs) that contain parasite-derived
RNA. However, the significance of the secreted RNA remains unexplored. Here, we …

The spike architecture of wheat plays a crucial role in determining grain number, making it a
key trait for optimization in wheat breeding programs. In this study, we used a multi-omic …

DNA modifications are critical in fine-tuning the biological processes in model organisms.
However, the presence of cytosine methylation (5mC) and the function of the putative DNA …

Background Plasmodium parasites undergo several major developmental transitions during
their complex lifecycle, which are enabled by precisely ordered gene expression programs …

Background Chromatin dysregulation is associated with developmental disorders and
cancer. Numerous methods for measuring genome-wide chromatin accessibility have been …