Systemic complications of acromegaly and the impact of the current treatment landscape: an update
MR Gadelha, L Kasuki, DST Lim… - Endocrine reviews, 2019 - academic.oup.com
Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …
increased mortality when not adequately treated. Substantial advances in acromegaly …
Acromegaly
P Chanson, S Salenave - Orphanet journal of rare diseases, 2008 - Springer
Acromegaly is an acquired disorder related to excessive production of growth hormone (GH)
and characterized by progressive somatic disfigurement (mainly involving the face and …
and characterized by progressive somatic disfigurement (mainly involving the face and …
American Association of Clinical Endocrinologists medical guidelines for clinical practice for the diagnosis and treatment of acromegaly-2011 update
L Katznelson, JLD Atkinson, DM Cook… - Endocrine …, 2011 - endocrinepractice.org
AACE= American Association of Clinical Endocrinologists; BEL=“best evidence” level;
BMD= bone mineral density; CPAP= continuous positive airway pressure; CPG= clinical …
BMD= bone mineral density; CPAP= continuous positive airway pressure; CPG= clinical …
Mortality in acromegaly: a metaanalysis
OM Dekkers, NR Biermasz, AM Pereira… - The Journal of …, 2008 - academic.oup.com
Context: Several studies have assessed mortality risk in patients treated for acromegaly. All
studies found a mortality that was higher than expected for the general population, but most …
studies found a mortality that was higher than expected for the general population, but most …
Prolonged diagnostic delay in acromegaly is associated with increased morbidity and mortality
D Esposito, O Ragnarsson… - European journal of …, 2020 - academic.oup.com
Context Clinical features of acromegaly develop insidiously. Its diagnosis may therefore be
delayed. Objective Our aim was to study diagnostic delay and its impact on morbidity and …
delayed. Objective Our aim was to study diagnostic delay and its impact on morbidity and …
Evaluation of health-related quality of life in patients with Cushing's syndrome with a new questionnaire
SM Webb, X Badia, MJ Barahona… - European journal of …, 2008 - academic.oup.com
Chronic exposure to hypercortisolism has significant impact on patient's health and health-
related quality of life (HRQoL), as demonstrated with generic questionnaires. We have …
related quality of life (HRQoL), as demonstrated with generic questionnaires. We have …
Morbidity after long-term remission for acromegaly: persisting joint-related complaints cause reduced quality of life
NR Biermasz, AM Pereira, JWA Smit… - The Journal of …, 2005 - academic.oup.com
Active acromegaly is associated with significant comorbidity and reduced quality of life.
However, the prevalence of comorbidity after long-term remission is not established …
However, the prevalence of comorbidity after long-term remission is not established …
Somatostatin analogues in acromegaly and gastroenteropancreatic neuroendocrine tumours: past, present and future
K Öberg, SWJ Lamberts - Endocrine-Related Cancer, 2016 - erc.bioscientifica.com
Acromegaly is a hormonal disorder that arises when the pituitary gland secretes excess
growth hormone (GH), which in turn stimulates a concomitant increase in serum insulin-like …
growth hormone (GH), which in turn stimulates a concomitant increase in serum insulin-like …
Quality of life (QoL) impairments in patients with a pituitary adenoma: a systematic review of QoL studies
CD Andela, M Scharloo, AM Pereira, AA Kaptein… - Pituitary, 2015 - Springer
Purpose Pituitary adenomas give rise to physical and psychological symptoms, which may
persist after biochemical cure. Growing attention has been paid to quality of life (QoL) in …
persist after biochemical cure. Growing attention has been paid to quality of life (QoL) in …
Subtle cognitive impairments in patients with long-term cure of Cushing's disease
J Tiemensma, NE Kokshoorn… - The Journal of …, 2010 - academic.oup.com
Abstract Context and Objective: Active Cushing's disease is associated with cognitive
impairments. We hypothesized that previous hypercortisolism in patients with Cushing's …
impairments. We hypothesized that previous hypercortisolism in patients with Cushing's …