Ferroptosis is a non-apoptotic cell death mechanism characterized by iron-dependent
membrane lipid peroxidation. Here, we review what is known about the cellular mechanisms …

Ferroptosis, an intricately regulated form of cell death characterized by uncontrolled lipid
peroxidation, has garnered substantial interest since this term was first coined in 2012 …

Ferroptosis is evolving as a highly promising approach to combat difficult-to-treat tumour
entities including therapy-refractory and dedifferentiating cancers,–. Recently, ferroptosis …

Ferroptosis, marked by iron-dependent lipid peroxidation, may present an Achilles heel for
the treatment of cancers. Ferroptosis suppressor protein-1 (FSP1), as the second ferroptosis …

Cellular quality control systems sense and mediate homeostatic responses to prevent the
buildup of aberrant macromolecules, which arise from errors during biosynthesis, damage …

Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …

Ferroptosis is a form of iron-related oxidative cell death governed by an integrated redox
system, encompassing pro-oxidative proteins and antioxidative proteins. These proteins …

Ferroptosis is inhibited by glutathione peroxidase 4 (GPX4), an antioxidant enzyme that
uses reduced glutathione (GSH) as a cofactor to detoxify lipid hydroperoxides. As a …

Ferroptosis, a form of non-apoptotic cell death that is hallmarked by lipid peroxidation of
cellular membranes, has gained considerable attention as it is considered a potential …

Macroautophagy/autophagy is a complex degradation process with a dual role in cell death
that is influenced by the cell types that are involved and the stressors they are exposed to …