Protein methylation is a key post-translational modification whose effects on gene
expression have been intensively studied over the last two decades. Recently, renewed …

Histidine methylation has been known for many years (Searle and Westall, 1951), but only a
few proteins carrying such modifications have been studied (Webb et al., 2010; Al-Hadid et …

Degrons are elements within protein substrates that mediate the interaction with specific
degradation machineries to control proteolysis. Recently, a few classes of C-terminal …

Actin is one of the most abundant and essential intracellular proteins that mediates nearly
every form of cellular movement and underlies such key processes as embryogenesis …

Fish skeletal muscles are composed of spatially well-separated fiber types, namely, red and
white muscles with different physiological functions and metabolism. To compare the DNA …

Protein methylation occurs predominantly on lysine and arginine residues, but histidine also
serves as a methylation substrate. However, a limited number of enzymes responsible for …

Dear Editor, Methylation is one of the most abundant and common posttranslational
modifications (PTMs) and plays important roles in a wide range of cellular events 1, 2 …

Protein methylation is one of the most common post-translational modifications observed in
basic amino acid residues, including lysine, arginine, and histidine. Histidine methylation …

In several carcinomas, the SET Domain Containing 3, Actin Histidine Methyltransferase
(SETD3) is associated with oncogenesis. However, there is little knowledge about the role of …

SETD3 belongs to a family of SET-domain containing proteins. Recently, SETD3 was found
as the first and so-far the only known metazoan histidine methyltransferase that catalyzes …