Natural product interventions for chemotherapy and radiotherapy-induced side effects

QY Zhang, FX Wang, KK Jia, LD Kong - Frontiers in pharmacology, 2018 - frontiersin.org
Cancer is the second leading cause of death in the world. Chemotherapy and radiotherapy
are the common cancer treatments. However, the development of adverse effects resulting …

Metal drugs and the anticancer immune response

B Englinger, C Pirker, P Heffeter, A Terenzi… - Chemical …, 2018 - ACS Publications
The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …

Molecular mechanisms of cardiomyocyte death in drug-induced cardiotoxicity

W Ma, S Wei, B Zhang, W Li - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
Homeostatic regulation of cardiomyocytes plays a crucial role in maintaining the normal
physiological activity of cardiac tissue. Severe cardiotoxicity results in cardiac diseases …

[HTML][HTML] Natural products as safeguards against monosodium glutamate-induced toxicity

MM Hajihasani, V Soheili, MR Zirak… - Iranian Journal of …, 2020 - ncbi.nlm.nih.gov
Monosodium glutamate is a sodium salt of a nonessential amino acid, L-glutamic acid,
which is widely used in food industry. Glutamate plays an important role in principal brain …

Radiation-assisted reduction of graphene oxide by aloe vera and ginger and their antioxidant and anti-inflammatory roles against male mice liver injury induced by …

MM Atta, ME Habieb, MAEH Mohamed… - New Journal of …, 2022 - pubs.rsc.org
A novel method for graphene oxide (GO) reduction using γ-rays in the presence of natural
antioxidants is revealed to be a promising eco-friendly and safe approach for producing …

Zingerone mitigates carrageenan-induced inflammation through antioxidant and anti-inflammatory activities

S Mehrzadi, H Khalili, I Fatemi, A Malayeri… - Inflammation, 2021 - Springer
Inflammation is the body's response against various pathogens and has a critical role in
numerous diseases. Zingerone (Zing), a bioactive substance derived from ginger root, has a …

Ameliorative and protective effects of ginger and its main constituents against natural, chemical and radiation-induced toxicities: A comprehensive review

MA Alsherbiny, WH Abd-Elsalam, E Taher… - Food and Chemical …, 2019 - Elsevier
Fatal unintentional poisoning is widespread upon human exposure to toxic agents such as
pesticides, heavy metals, environmental pollutants, bacterial and fungal toxins or even some …

[HTML][HTML] Murine models of radiation cardiotoxicity: A systematic review and recommendations for future studies

GM Walls, R O'Kane, M Ghita, R Kuburas… - Radiotherapy and …, 2022 - Elsevier
Background and purpose The effects of radiation on the heart are dependent on dose,
fractionation, overall treatment time, and pre-existing cardiovascular pathology. Murine …

[HTML][HTML] Experimental evidence of the neurotoxic effect of monosodium glutamate in adult female Sprague Dawley rats: The potential protective role of Zingiber …

SA El-Hashash, MA El-Sakhawy, HSE Eldamaty… - Saudi Journal of …, 2023 - Elsevier
Strategies to prevent the health abnormalities associated with the extensive use of MSG
(monosodium glutamate) as a flavoring booster are badly needed. The current study was …

Zingerone targets status epilepticus by blocking hippocampal neurodegeneration via regulation of redox imbalance, inflammation and apoptosis

S Rashid, AF Wali, SM Rashid, RM Alsaffar, A Ahmad… - Pharmaceuticals, 2021 - mdpi.com
Epilepsy is an intricate neurological disease where the neurons are severely affected,
leading to the mortality of millions worldwide. Status epilepticus (SE), induced by lithium …