Cardiac fibroblasts are the primary cell type responsible for deposition of extracellular matrix
in the heart, providing support to the contracting myocardium and contributing to a myriad of …

Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …

Myocardial infarction (MI) leads to a multi-phase reparative process at the site of damaged
heart that ultimately results in the formation of non-conductive fibrous scar tissue. Despite …

Abstract Development of cardiac fibrosis and arrhythmias is controlled by the activity of and
communication between cardiomyocytes and fibroblasts in the heart. Myocyte-fibroblast …

Cardiac fibroblasts constitute a major cell population in the heart. They secrete extracellular
matrix components and various other factors shaping the microenvironment of the heart. In …

Three‐dimensional bioprinting is an innovative technique in tissue engineering, to create
layer‐by‐layer structures, required for mimicking body tissues. However, synthetic bioinks …

Annually, approximately 17 million people die from cardiovascular diseases worldwide, half
of them suddenly. The most common direct cause of sudden cardiac death is ventricular …

Background: Atrial fibrillation (AF), the most common cardiac arrhythmia, is characterized by
alteration of the action potential (AP) propagation. Under persistent AF, myocytes undergo …

Fibroblasts are an important resident cell population in the heart involved in maintaining
homeostasis and structure during normal conditions. They are also crucial in disease states …

Atrial myocardial degeneration predisposes to atrial fibrillation (AF), ischemic stroke, and
heart failure. Studies suggest the presence of gender differences in atrial myocardial …