[HTML][HTML] Glycosylation in extracellular vesicles: Isolation, characterization, composition, analysis and clinical applications
V Vrablova, N Kosutova, A Blsakova, A Bertokova… - Biotechnology …, 2023 - Elsevier
This review provides a comprehensive overview of our understanding of the role that
glycans play in the formation, loading and release of extracellular vesicles (EVs). The …
glycans play in the formation, loading and release of extracellular vesicles (EVs). The …
[HTML][HTML] Lectins as potential tools for cancer biomarker discovery from extracellular vesicles
Extracellular vesicles (EVs) have considerable potential as diagnostic, prognostic, and
therapeutic agents, in large part because molecular patterns on the EV surface betray the …
therapeutic agents, in large part because molecular patterns on the EV surface betray the …
[HTML][HTML] Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade
Aberrant glycosylation is a crucial strategy employed by cancer cells to evade cellular
immunity. However, it's unclear whether homologous recombination (HR) status-dependent …
immunity. However, it's unclear whether homologous recombination (HR) status-dependent …
Therapeutic Applications of Stem Cell-Derived Exosomes
OAAY Abdulmalek, KH Husain, HKAA AlKhalifa… - International Journal of …, 2024 - mdpi.com
Exosomes are extracellular vesicles of endosomal origin, ranging from 30 to 150 nm in
diameter, that mediate intercellular transfer of various biomolecules, such as proteins, lipids …
diameter, that mediate intercellular transfer of various biomolecules, such as proteins, lipids …
[HTML][HTML] Targeting protein glycosylation to regulate inflammation in the respiratory tract: novel diagnostic and therapeutic candidates for chronic respiratory diseases
X Xie, S Kong, W Cao - Frontiers in Immunology, 2023 - frontiersin.org
Protein glycosylation is a widespread posttranslational modification that can impact the
function of proteins. Dysregulated protein glycosylation has been linked to several diseases …
function of proteins. Dysregulated protein glycosylation has been linked to several diseases …
Magnetic nanoagent assisted deciphering of heterogeneous glycans in extracellular vesicles of varied cellular origins
Y Yan, R Li, H Chen, Y Li, M Wu, Z Wang… - Biosensors and …, 2023 - Elsevier
Extracellular vesicles bear a rich glycome that presents versatile functions in diverse
biological processes. Leverage polydopamine modified magnetic particles to serve as …
biological processes. Leverage polydopamine modified magnetic particles to serve as …
Identification of animal species of origin in meat based on glycopeptide analysis by UPLC–QTOF-MS
J Tai, H Hu, X Cao, X Liang, Y Lu, H Zhang - Analytical and Bioanalytical …, 2023 - Springer
Adulteration of meat and meat products causes a concerning threat for consumers. It is
necessary to develop novel robust and sensitive methods which can authenticate the origin …
necessary to develop novel robust and sensitive methods which can authenticate the origin …
[HTML][HTML] Large-scale column-free purification of bovine F-ATP synthase
C Jiko, Y Morimoto, T Tsukihara, C Gerle - Journal of Biological Chemistry, 2024 - ASBMB
Mammalian F-ATP synthase is central to mitochondrial bioenergetics and is present in the
inner mitochondrial membrane in a dynamic oligomeric state of higher oligomers, tetramers …
inner mitochondrial membrane in a dynamic oligomeric state of higher oligomers, tetramers …
Dielectrophoretic Capture of Cancer‐Derived Small‐Extracellular‐Vesicle‐Bound Janus Nanoparticles via Lectin–Glycan Interaction
Y Choi, K Akyildiz, J Seong, Y Lee… - Advanced …, 2024 - Wiley Online Library
Glycosylation is closely related to cellular metabolism and disease progression. In particular,
glycan levels in cancer cells and tissues increase during cancer progression. This …
glycan levels in cancer cells and tissues increase during cancer progression. This …
[HTML][HTML] Cell Membrane Sialome: Sialic Acids as Therapeutic Targets and Regulators of Drug Resistance in Human Cancer Management
P Jastrząb, K Narejko, H Car, P Wielgat - Cancers, 2023 - mdpi.com
Simple Summary The aberrant sialylation of membrane glycocalyx plays a pivotal role in the
regulation of malignant cell behavior and correlates with a worse prognosis and shorter …
regulation of malignant cell behavior and correlates with a worse prognosis and shorter …