The Groebke‐Blackburn‐Bienaymé Reaction
A Boltjes, A Dömling - European Journal of Organic Chemistry, 2019 - Wiley Online Library
Imidazo [1, 2‐a] pyridine is a well‐known scaffold in many marketed drugs, such as
Zolpidem, Minodronic acid, Miroprofen and DS‐1 and it also serves as a broadly applied …
Zolpidem, Minodronic acid, Miroprofen and DS‐1 and it also serves as a broadly applied …
Isocyanide-based multicomponent reactions for the synthesis of heterocycles
Multicomponent reactions (MCRs) are extremely popular owing to their facile execution,
high atom-efficiency and the high diversity of products. MCRs can be used to access various …
high atom-efficiency and the high diversity of products. MCRs can be used to access various …
Pyrimidazole-based covalent organic frameworks: integrating functionality and ultrastability via isocyanide chemistry
J Liu, T Yang, ZP Wang, PL Wang, J Feng… - Journal of the …, 2020 - ACS Publications
Development of new chemistry to simultaneously meet the demands for topology,
connectivity, and functionality is highly desired in the research area of covalent organic …
connectivity, and functionality is highly desired in the research area of covalent organic …
Groebke–Blackburn–Bienaymé multicomponent reaction: emerging chemistry for drug discovery
S Shaaban, BF Abdel-Wahab - Molecular diversity, 2016 - Springer
Abstract The Groebke–Blackburn–Bienaymé reaction (GBBR) is used for the one-pot
synthesis of therapeutically relevant fused imidazoles bridgehead nitrogen heterocyclic …
synthesis of therapeutically relevant fused imidazoles bridgehead nitrogen heterocyclic …
Synthesis of imidazopyridines from the Morita–Baylis–Hillman acetates of nitroalkenes and convenient access to Alpidem and Zolpidem
DK Nair, SM Mobin, INN Namboothiri - Organic letters, 2012 - ACS Publications
A variety of functionalized imidazo [1, 2-a] pyridines have been synthesized through a one-
pot, room temperature, and reagent-free reaction between MBH acetates of nitroalkenes and …
pot, room temperature, and reagent-free reaction between MBH acetates of nitroalkenes and …
Imidazo [1, 2-a] pyridine scaffold as prospective therapeutic agents
Imidazo [1, 2-a] pyridine is one of the most potential bicyclic 5–6 heterocyclic rings that is
recognized as a “drug prejudice” scaffold due to its broad range of applications in medicinal …
recognized as a “drug prejudice” scaffold due to its broad range of applications in medicinal …
Synthesis and site selective C–H functionalization of imidazo-[1, 2-a] pyridines
Imidazo [1, 2-a] pyridine has gained much interest in the field of drug development because
of its strong medicinal properties, therefore the discovery of novel methods for its synthesis …
of its strong medicinal properties, therefore the discovery of novel methods for its synthesis …
Diversity-oriented synthesis of fused-imidazole derivatives via Groebke–Blackburn–Bienayme reaction: a review
In recent time, diversity-oriented synthesis of small chemical entities has been emerged as a
possible tool for exploring the intersections between chemistry and biology. These small …
possible tool for exploring the intersections between chemistry and biology. These small …
Imidazopyridine, a promising scaffold with potential medicinal applications and structural activity relationship (SAR): recent advances
Imidazopyridine scaffold has gained tremendous importance over the past few decades.
Imidazopyridines have been expeditiously used for the rationale design and development of …
Imidazopyridines have been expeditiously used for the rationale design and development of …
Microwave-assisted multicomponent reactions in heterocyclic chemistry and mechanistic aspects
S Gulati, SE John… - Beilstein Journal of Organic …, 2021 - beilstein-journals.org
Microwave-assisted (MWA) multicomponent reactions (MCRs) have successfully emerged
as one of the useful tools in the synthesis of biologically relevant heterocycles. These …
as one of the useful tools in the synthesis of biologically relevant heterocycles. These …