Suicide is a worldwide phenomenon. This review is based on a literature search of the
World Health Organization (WHO) databases and PubMed. According to the WHO, in 2015 …

The transition from acute to chronic pain appears to occur in discrete pathophysiological and
histopathological steps. Stimuli initiating a nociceptive response vary, but receptors and …

Background Pain is an enormous problem globally. Estimates suggest that 20% of adults
suffer from pain globally and 10% are newly diagnosed with chronic pain each year …

A cross-sectional, Internet-based survey was conducted in a nationally representative
sample of United States (US) adults to estimate the point prevalence of chronic pain and to …

This large scale computer-assisted telephone survey was undertaken to explore the
prevalence, severity, treatment and impact of chronic pain in 15 European countries and …

The role of the brain in chronic pain conditions remains speculative. We compared brain
morphology of 26 chronic back pain (CBP) patients to matched control subjects, using …

This article surveys worldwide medical, ethical, and legal trends and initiatives related to the
concept of pain management as a human right. This concept recently gained momentum …

Long‐term opioid management for chronic noncancer pain - Noble, M - 2010 | Cochrane
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Living with unrelenting pain (chronic pain) is maladaptive and is thought to be associated
with physiological and psychological modifications, yet there is a lack of knowledge …

The problem of abuse of and addiction to opioid analgesics has emerged as a major issue
for the United States in the past decade and has worsened over the past few years. The …