Glutamine: metabolism and immune function, supplementation and clinical translation

V Cruzat, M Macedo Rogero, K Noel Keane, R Curi… - Nutrients, 2018 - mdpi.com
Glutamine is the most abundant and versatile amino acid in the body. In health and disease,
the rate of glutamine consumption by immune cells is similar or greater than glucose. For …

ISSN exercise & sports nutrition review update: research & recommendations

CM Kerksick, CD Wilborn, MD Roberts… - Journal of the …, 2018 - Springer
Background Sports nutrition is a constantly evolving field with hundreds of research papers
published annually. In the year 2017 alone, 2082 articles were published under the key …

Glutamine as an anti-fatigue amino acid in sports nutrition

AY Coqueiro, MM Rogero, J Tirapegui - Nutrients, 2019 - mdpi.com
Glutamine is a conditionally essential amino acid widely used in sports nutrition, especially
because of its immunomodulatory role. Notwithstanding, glutamine plays several other …

Amino acid supplementation and impact on immune function in the context of exercise

VF Cruzat, M Krause, P Newsholme - … of the international Society of Sports …, 2014 - Springer
Moderate and chronic bouts of exercise may lead to positive metabolic, molecular, and
morphological adaptations, improving health. Although exercise training stimulates the …

Aspectos atuais sobre estresse oxidativo, exercícios físicos e suplementação

VF Cruzat, MM Rogero, MC Borges… - Revista Brasileira de …, 2007 - SciELO Brasil
As espécies reativas de oxigênio (ERO) são normalmente produzidas pelo metabolismo
corporal. Todavia, ERO apresentam a capacidade de retirar elétrons de outros compostos …

Amino acids regulating skeletal muscle metabolism: mechanisms of action, physical training dosage recommendations and adverse effects

G Li, Z Li, J Liu - Nutrition & Metabolism, 2024 - Springer
Maintaining skeletal muscle mass is important for improving muscle strength and function.
Hence, maximizing lean body mass (LBM) is the primary goal for both elite athletes and …

Determination of the anti-inflammatory and cytoprotective effects of l-glutamine and l-alanine, or dipeptide, supplementation in rats submitted to resistance exercise

R Raizel, JSM Leite, TM Hypólito… - British journal of …, 2016 - cambridge.org
We evaluated the effects of chronic oral supplementation with l-glutamine and l-alanine in
their free form or as the dipeptide l-alanyl-l-glutamine (DIP) on muscle damage …

Effects of supplementation with free glutamine and the dipeptide alanyl‐glutamine on parameters of muscle damage and inflammation in rats submitted to prolonged …

VF Cruzat, MM Rogero… - Cell Biochemistry and …, 2010 - Wiley Online Library
In this study, we investigated the effect of the supplementation with the dipeptide l‐alanyl‐l‐
glutamine (DIP) and a solution containing l‐glutamine and l‐alanine on plasma levels …

[HTML][HTML] Oral free and dipeptide forms of glutamine supplementation attenuate oxidative stress and inflammation induced by endotoxemia

VF Cruzat, A Bittencourt, SP Scomazzon, JSM Leite… - Nutrition, 2014 - Elsevier
Objective The aim of the present study was to determine the effects of oral supplementation
with l-glutamine plus l-alanine (GLN+ ALA), both in the free form and l-alanyl-l-glutamine …

Oral supplementations with free and dipeptide forms of L-glutamine in endotoxemic mice: effects on muscle glutamine-glutathione axis and heat shock proteins

VF Cruzat, LC Pantaleão, J Donato Jr… - The Journal of nutritional …, 2014 - Elsevier
Sepsis is a leading cause of death in intensive care units worldwide. Low availability of
glutamine contributes to the catabolic state of sepsis. l-Glutamine supplementation has …