[HTML][HTML] Genetic predictors of human chronic pain conditions

K Zorina-Lichtenwalter, CB Meloto, S Khoury… - Neuroscience, 2016 - Elsevier
Chronic pain conditions are multifactorial disorders with a high frequency in the population.
Their pathophysiology is often unclear, and treatment is inefficient. During the last 20 years …

Risk factors for bruxism

M Kuhn, JC Türp - SWISS DENTAL JOURNAL SSO–Science …, 2018 - swissdentaljournal.org
The aim of the present study was to summarize the risk factors for bruxism that were
identified by a systematic search of the literature published between 2007 and 2016 …

Are catechol-O-methyltransferase gene polymorphisms genetic markers for pain sensitivity after all?–a review and meta-analysis

A Vetterlein, M Monzel, M Reuter - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
The catechol-O-methyltransferase (COMT) gene has arguably been the designated pain
sensitivity gene for nearly two decades. However, the literature provides inconsistent …

NaV1. 7 as a pharmacogenomic target for pain: moving toward precision medicine

Y Yang, MA Mis, M Estacion, SD Dib-Hajj… - Trends in …, 2018 - cell.com
Chronic pain is a global unmet medical need. Most existing treatments are only partially
effective or have side effects that limit their use. Rapid progress in elucidating the …

Heart rate variability responses to cognitive stress in fibromyalgia are characterised by inadequate autonomous system stress responses: a clinical trial

T Zetterman, R Markkula, T Miettinen, E Kalso - Scientific reports, 2023 - nature.com
Fibromyalgia (FM) is associated with sympathetically dominant dysautonomia, but the
connection between dysautonomia and FM symptoms is unclear. Dysautonomia can be …

[PDF][PDF] Genetic addiction risk score (GARS)™, a predictor of vulnerability to opioid dependence

K Blum, ALC Chen, PK Thanos, M Febo… - Front Biosci (Elite …, 2018 - academia.edu
175 1. ABSTRACT Genetic addiction risk score (GARS) ™, a predictor of vulnerability to opioid
dependence Kenneth Blum1-8,10,18 Page 1 175 1. ABSTRACT The interaction of …

The genetics of pain: implications for therapeutics

JE Sexton, JJ Cox, J Zhao… - Annual review of …, 2018 - annualreviews.org
Pain is an increasing clinical challenge affecting about half the population, with a substantial
number of people suffering daily intense pain. Such suffering can be linked to the dramatic …

Burning mouth syndrome and hypertension: Prevalence, gender differences and association with pain and psycho-social characteristics—A case control study

D Adamo, F Canfora, E Calabria, N Coppola… - International Journal of …, 2023 - mdpi.com
Background: To assess the prevalence of hypertension (HTN) in burning mouth syndrome
(BMS) patients and to investigate its relationship with sociodemographic factors, pain and …

Rare variant analyses in large-scale cohorts identified SLC13A1 associated with chronic pain

X Ao, M Parisien, M Zidan, AV Grant, AE Martinsen… - Pain, 2023 - journals.lww.com
Chronic pain is a prevalent disease with increasing clinical challenges. Genome-wide
association studies in chronic pain patients have identified hundreds of common pathogenic …

Genetics and opioids: towards more appropriate prescription in cancer pain

D Bugada, LF Lorini, R Fumagalli, M Allegri - Cancers, 2020 - mdpi.com
Opioids are extensively used in patients with cancer pain; despite their efficacy, several
patients can experience ineffective analgesia and/or side effects. Pharmacogenetics is a …