Oxidative Stress Modulation and ROS‐Mediated Toxicity in Cancer: A Review on In Vitro Models for Plant‐Derived Compounds

MJ Vallejo, L Salazar, M Grijalva - Oxidative Medicine and …, 2017 - Wiley Online Library
Medicinal and aromatic plants (MAPs) are known and have been long in use for a variety of
health and cosmetics applications. Potential pharmacological usages that take advantage of …

Quantitative phase imaging for label-free analysis of cancer cells—focus on digital holographic microscopy

Z El-Schich, A Leida Mölder, A Gjörloff Wingren - Applied Sciences, 2018 - mdpi.com
To understand complex biological processes, scientists must gain insight into the function of
individual living cells. In contrast to the imaging of fixed cells, where a single snapshot of the …

High accuracy label-free classification of single-cell kinetic states from holographic cytometry of human melanoma cells

M Hejna, A Jorapur, JS Song, RL Judson - Scientific reports, 2017 - nature.com
Digital holographic cytometry (DHC) permits label-free visualization of adherent cells.
Dozens of cellular features can be derived from segmentation of hologram-derived images …

On-chip label-free cell classification based directly on off-axis holograms and spatial-frequency-invariant deep learning

M Dudaie, I Barnea, N Nissim, NT Shaked - Scientific Reports, 2023 - nature.com
We present a rapid label-free imaging flow cytometry and cell classification approach based
directly on raw digital holograms. Off-axis holography enables real-time acquisition of cells …

Label-free assessment of the drug resistance of epithelial ovarian cancer cells in a microfluidic holographic flow cytometer boosted through machine learning

L Xin, W Xiao, L Che, JJ Liu, L Miccio, V Bianco… - ACS …, 2021 - ACS Publications
About 75% of epithelial ovarian cancer (EOC) patients suffer from relapsing and develop
drug resistance after primary chemotherapy. The commonly used clinical examinations and …

Exploiting the potential of commercial digital holographic microscopy by combining it with 3D matrix cell culture assays

M Hellesvik, H Øye, H Aksnes - Scientific Reports, 2020 - nature.com
Abstract 3D cell culture assays are becoming increasingly popular due to their higher
resemblance to tissue environment. These provide an increased complexity compared to the …

Evaluation of the impact of imprinted polymer particles on morphology and motility of breast cancer cells by using digital holographic cytometry

M Patel, M Feith, B Janicke, K Alm, Z El-Schich - Applied Sciences, 2020 - mdpi.com
Breast cancer is the second most common cancer type worldwide and breast cancer
metastasis accounts for the majority of breast cancer-related deaths. Tumour cells produce …

Label-free classification of apoptosis, ferroptosis and necroptosis using digital holographic cytometry

KL Barker, KM Boucher, RL Judson-Torres - Applied Sciences, 2020 - mdpi.com
Featured Application Digital holographic cytometry for classification of programmed cell
death. Abstract Apoptosis, ferroptosis and necroptosis are three distinct forms of …

Whole-cell multiparameter assay for ricin and abrin activity-based digital holographic microscopy

E Makdasi, O Laskar, E Milrot, O Schuster, S Shmaya… - Toxins, 2019 - mdpi.com
Ricin and abrin are ribosome-inactivating proteins leading to inhibition of protein synthesis
and cell death. These toxins are considered some of the most potent and lethal toxins …

Evaluation of holographic imaging cytometer holomonitor M4® motility applications

Y Zhang, RL Judson - Cytometry Part A, 2018 - Wiley Online Library
Digital holographic cytometry (DHC) and other methods of quantitative phase imaging
permit extended time‐lapse imaging of mammalian cells in the absence of induced cellular …