The nanoparticle biomolecule corona: lessons learned–challenge accepted?
D Docter, D Westmeier, M Markiewicz… - Chemical Society …, 2015 - pubs.rsc.org
Besides the wide use of engineered nanomaterials (NMs) in technical products, their
applications are not only increasing in biotechnology and biomedicine, but also in the …
applications are not only increasing in biotechnology and biomedicine, but also in the …
Artificial intelligence and machine learning empower advanced biomedical material design to toxicity prediction
AV Singh, D Rosenkranz, MHD Ansari… - Advanced Intelligent …, 2020 - Wiley Online Library
Materials at the nanoscale exhibit specific physicochemical interactions with their
environment. Therefore, evaluating their toxic potential is a primary requirement for …
environment. Therefore, evaluating their toxic potential is a primary requirement for …
Protein bio-corona: critical issue in immune nanotoxicology
With the expansion of the nanomedicine field, the knowledge focusing on the behavior of
nanoparticles in the biological milieu has rapidly escalated. Upon introduction to a complex …
nanoparticles in the biological milieu has rapidly escalated. Upon introduction to a complex …
Nexus between in silico and in vivo models to enhance clinical translation of nanomedicine
In cancer, one of the main barriers to effective chemotherapy is inefficient drug delivery. The
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
Liposome–protein corona in a physiological environment: challenges and opportunities for targeted delivery of nanomedicines
G Caracciolo - Nanomedicine: Nanotechnology, Biology and Medicine, 2015 - Elsevier
Active targeting that exploits the (over) expression of surface receptors in target cells by
ligand incorporation is a central concept in nanomedicine research. Despite unprecedented …
ligand incorporation is a central concept in nanomedicine research. Despite unprecedented …
The effect of surface charge of functionalized Fe3O4 nanoparticles on protein adsorption and cell uptake
MP Calatayud, B Sanz, V Raffa, C Riggio, MR Ibarra… - Biomaterials, 2014 - Elsevier
Nanoparticles engineered for biomedical applications are meant to be in contact with protein-
rich physiological fluids. These proteins are usually adsorbed onto the nanoparticle's …
rich physiological fluids. These proteins are usually adsorbed onto the nanoparticle's …
Mathematical modeling in cancer nanomedicine: a review
Cancer continues to be among the leading healthcare problems worldwide, and efforts
continue not just to find better drugs, but also better drug delivery methods. The need for …
continue not just to find better drugs, but also better drug delivery methods. The need for …
Materials, surfaces, and interfacial phenomena in nanoplastics toxicology research
LMA Martin, N Gan, E Wang, M Merrill, W Xu - Environmental Pollution, 2022 - Elsevier
In response to the growing worldwide plastic pollution problem, the field of nanoplastics
research is attempting to determine the risk of exposure to nanoparticles amidst their ever …
research is attempting to determine the risk of exposure to nanoparticles amidst their ever …
Adsorption and unfolding of a single protein triggers nanoparticle aggregation
The response of living systems to nanoparticles is thought to depend on the protein corona,
which forms shortly after exposure to physiological fluids and which is linked to a wide array …
which forms shortly after exposure to physiological fluids and which is linked to a wide array …
Engineered nanomaterial uptake and tissue distribution: from cell to organism
H Kettiger, A Schipanski, P Wick… - International journal of …, 2013 - Taylor & Francis
Improved understanding of interactions between nanoparticles and biological systems is
needed to develop safety standards and to design new generations of nanomaterials. This …
needed to develop safety standards and to design new generations of nanomaterials. This …