The placenta is essential for normal in utero development in mammals. In humans, defective
placental formation underpins common pregnancy disorders such as pre-eclampsia and …

The placenta is an ephemeral but critical organ for the survival of all eutherian mammals
and marsupials. It is the primary messenger system between the mother and fetus, where …

In this review, we comprehensively present the function of epigenetic regulations in normal
placental development as well as in a prominent disease of placental origin, preeclampsia …

MicroRNAs (miRNAs) constitute a large family of small noncoding RNAs that are encoded
by the genomes of most organisms. They regulate gene expression through …

Children, because of having an immature immune system, are usually more prone than the
adults to the microbial infections and have more severe symptoms, which is especially true …

MicroRNAs are small noncoding RNAs responsible for regulating 40% to 60% of gene
expression at the posttranscriptional level. The discovery of circulating microRNAs in several …

Extracellular vesicles (EVs) play a crucial role in pregnancy, revealed by the presence of
placental‐derived EVs in maternal blood, their in vitro functionality, and their altered cargo in …

During the pregnancy associated syndrome preeclampsia (PE), there is increased release
of placental syncytiotrophoblast extracellular vesicles (STBEVs) and free foetal haemoglobin …

At term, the signals of fetal maturity and feto-placental tissue aging prompt uterine readiness
for delivery by transitioning quiescent myometrium to an active stage. It is still unclear how …

In mammals, the expression of a subset of microRNA (miRNA) genes is governed by
genomic imprinting, an epigenetic mechanism that confers monoallelic expression in a …