[HTML][HTML] Treatment of inflammatory bowel disease: a comprehensive review

Z Cai, S Wang, J Li - Frontiers in medicine, 2021 - frontiersin.org
Inflammatory bowel disease (IBD), as a global disease, has attracted much research
interest. Constant research has led to a better understanding of the disease condition and …

The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

[HTML][HTML] Guselkumab for the treatment of Crohn's disease: induction results from the phase 2 GALAXI-1 study

WJ Sandborn, GR D'Haens, W Reinisch, J Panés… - Gastroenterology, 2022 - Elsevier
Background & Aims Guselkumab, a selective p19 interleukin-23 antagonist, is approved for
the treatment of plaque psoriasis and psoriatic arthritis. This study evaluated the efficacy and …

Crosstalk of inflammatory cytokines within the breast tumor microenvironment

O Habanjar, R Bingula, C Decombat… - International journal of …, 2023 - mdpi.com
Several immune and immunocompetent cells, including dendritic cells, macrophages,
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …

Transferable immunoglobulin A–Coated Odoribacter splanchnicus in responders to fecal microbiota transplantation for ulcerative colitis limits colonic inflammation

SF Lima, L Gogokhia, M Viladomiu, L Chou, G Putzel… - Gastroenterology, 2022 - Elsevier
Background & Aims Fecal microbiota transplantation (FMT) is an emerging treatment
modality for ulcerative colitis (UC). Several randomized controlled trials have shown efficacy …

Cytokine-mediated crosstalk between immune cells and epithelial cells in the gut

M Mahapatro, L Erkert, C Becker - Cells, 2021 - mdpi.com
Cytokines are small proteins that are secreted by a vast majority of cell types in the gut. They
not only establish cell-to-cell interactions and facilitate cellular signaling, but also regulate …

emerging drug therapies in inflammatory bowel disease

LB Grossberg, K Papamichael… - Alimentary …, 2022 - Wiley Online Library
Background The landscape of inflammatory bowel disease (IBD) treatment is rapidly
expanding with the development of new therapeutic options. Aim To review the mechanisms …

Neurogenesis is disrupted in human hippocampal progenitor cells upon exposure to serum samples from hospitalized COVID-19 patients with neurological symptoms

A Borsini, B Merrick, J Edgeworth, G Mandal… - Molecular …, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), represents an enormous new threat to our
healthcare system and particularly to the health of older adults. Although the respiratory …

The role of intestinal microbes on intestinal barrier function and host immunity from a metabolite perspective

Y Fu, J Lyu, S Wang - Frontiers in immunology, 2023 - frontiersin.org
The gut is colonized by many commensal microorganisms, and the diversity and metabolic
patterns of microorganisms profoundly influence the intestinal health. These microbial …

Perspective insights of small molecules, phytoconstituents and biologics in the management of psoriasis: A focus on targeting major inflammatory cytokine pathways

H Kadagothy, S Nene, E Amulya, G Vambhurkar… - European Journal of …, 2023 - Elsevier
Psoriasis is an enduring, pruritic and papulosquamous skin ailment that poses a significant
burden on public health. It is mainly characterized by hyperkeratosis, acanthosis …