The intestine represents one of the first barriers where microorganisms and environmental
antigens come into tight contact with the host immune system. A healthy intestine is essential …

With the ulcerative colitis (UC) incidence increasing worldwide, it is of great importance to
prevent and treat UC. However, efficient treatment options for UC are relatively limited. Due …

A subset of Nucleotide-binding and leucine-rich repeat-containing receptors (NLRs) function
to mitigate overzealous pro-inflammatory signaling produced by NF-κB activation. Under …

The gut microbiota plays a key role in host metabolic thermogenesis by activating UCP1 and
increasing the browning process of white adipose tissue (WAT), especially in cold …

Diet is a modifiable, noninvasive, inexpensive behavior that is crucial in shaping the
intestinal microbiome. A microbiome “imbalance” or dysbiosis in inflammatory bowel …

Simple Summary The commensal microbiome in the human body must always be
considered as a potential factor in carcinogenesis that may play a crucial role in the …

Background Obesity is a metabolic chronic disease with important associated morbidities
and mortality. Bariatric surgery is the most effective treatment for maintaining long-term …

Vitamin D deficiency, a growing public health problem, is associated with elevated serum
pro-inflammatory cytokines and gut microbial dysbiosis. Lactoferrin (LF), a strongly cationic …

Colorectal cancer (CRC) is one of the most frequent gastrointestinal malignant tumors
worldwide. Immune checkpoint therapies (ICTs) have been proven to be a reliable treatment …

Obesity (OB) is a metabolic chronic disease with a growing incidence and elevated
morbidities and mortality [1, 2]. OB is also associated with elevated economic costs for the …