Fibrinogen conversion into insoluble fibrin and the formation of a stable clot is the final step
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …

Post-acute sequelae of COVID (PASC), usually referred to as 'Long COVID'(a phenotype of
COVID-19), is a relatively frequent consequence of SARS-CoV-2 infection, in which …

Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Background Severe COVID‐19 disease is associated with thrombotic complications and
extensive fibrin deposition. This study investigates whether the hemostatic complications in …

Die Deutsche Gesellschaft für Pneumologie hat 2021 die AWMF S1-Leitlinie Long-/Post-
COVID initiiert. In einem breiten interdisziplinären Ansatz wurde diese S1-Leitlinie …

Earlier variants of SARS-CoV-2 have been associated with hypercoagulability and an
extensive formation of fibrin amyloid microclots, which are considered to contribute to the …

Platelet–endothelial interactions have a critical role in microcirculatory function, which
maintains tissue homeostasis. The subtle equilibrium between platelets and the vessel wall …

Abstract Purpose of Review Cardiac consequences occur in both acute COVID-19 and post-
acute sequelae of COVID-19 (PASC). Here, we highlight the current understanding about …

Clot retraction is important for the prevention of bleeding, in the manifestations of thrombosis
and for tissue repair. The molecular mechanisms behind clot formation are complex. Platelet …

Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the highly
pathogenic and highly transmissible human coronavirus that is the causative agent for the …