Food intake is mediated, in part, through brain pathways for motivation and reinforcement.
Dysregulation of these pathways may underlay some of the behaviors exhibited by patients …

First, work presented in this review strongly supports the notion that food addiction is a real
phenomenon. Second, although food and drugs of abuse act on the same central networks …

Presents the State-of-the-Art in Fat Taste TransductionA bite of cheese, a few potato chips, a
delectable piece of bacon-a small taste of high-fat foods often draws you back for more. But …

The distinction between natural addiction and drug addiction is interesting from many points
of view, including scientific and medical perspectives.“Natural addictions” are those based …

This paper is the 29th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning 30 years of research. It summarizes papers …

The nucleus accumbens (NAc) contains a hedonic hotspot in the rostral half of medial shell,
where opioid agonist microinjections are known to enhance positive hedonic orofacial …

Food intake, which is a highly reinforcing behavior, provides nutrients required for survival in
all animals. However, when fat and sugar consumption goes beyond the daily needs, it can …

Although they comprise only a small portion of the neurons in the region, cholinergic
interneurons in the dorsal striatum appear to play an important role in the regulation of …

The neurobiology of post-traumatic stress disorder (PTSD) remains unclear. Intense stress
promotes PTSD, which has been associated with exaggerated startle and deficient …

Opioid transmission and dysregulated prefrontal cortex (PFC) activity have both been
implicated in the inhibitory-control deficits associated with addiction and binge-type eating …