Protein Tyrosine Phosphatases in Neuroblastoma: Emerging Roles as Biomarkers and Therapeutic Targets

CE Nunes-Xavier, L Zaldumbide, L Mosteiro… - Frontiers in Cell and …, 2021 - frontiersin.org
Neuroblastoma is a type of cancer intimately related with early development and
differentiation of neuroendocrine cells, and constitutes one of the pediatric cancers with …

Genome-wide analysis identifies critical DNA methylations within NTRKs genes in colorectal cancer

Z Chen, Z Huang, Y Luo, Q Zou, L Bai, G Tang… - Journal of Translational …, 2021 - Springer
Background Neurotrophic tropomyosin receptor kinases (NTRKs) are a gene family function
as oncogene or tumor suppressor gene in distinct cancers. We aimed to investigate the …

Tumour targetable and microenvironment-responsive nanoparticles simultaneously disrupt the PD-1/PD-L1 pathway and MAPK/ERK/JNK pathway for efficient …

Y Li, M Qi, F Ding, Y Lv, J Ma, Y Zhu - Journal of Drug Targeting, 2021 - Taylor & Francis
The present study was aimed to develop a novel combination therapeutic strategy of gene
therapy and immunotherapy for efficiently treatment of colorectal cancer (CRC). To achieve …

[HTML][HTML] Analysis of SARS-CoV-2 infection associated cell entry proteins ACE2, CD147, PPIA, and PPIB in datasets from non SARS-CoV-2 infected neuroblastoma …

B Bergsneider, E Bailey, Y Ahmed, N Gogineni… - … and Biophysics Reports, 2021 - Elsevier
SARS-CoV-2 viral contagion has given rise to a worldwide pandemic. Although most
children experience minor symptoms from SARS-CoV-2 infection, some have severe …

YTHDC1 inhibits osteoclast differentiation to alleviate osteoporosis by enhancing PTPN6 messenger RNA stability in an m6A-hUR–dependent manner

M Zhang, J Guan, S Yu, Y Zhang… - Journal of Leukocyte …, 2024 - academic.oup.com
YTHDC1 has been confirmed to mediate osteoporosis (OP) progression by regulating
osteogenic differentiation. However, whether YTHDC1 mediates osteoclast differentiation …

A Potential Prognostic Gene Signature Associated with p53-Dependent NTRK1 Activation and Increased Survival of Neuroblastoma Patients

D Currie, N Wong, I Zane, T Rix, M Vardakastanis… - Cancers, 2024 - mdpi.com
Simple Summary Neuroblastomas are the most frequent neoplasms of infancy worldwide,
accounting for 8% to 10% of all childhood cancers. Long-term survival with high-risk-type …

SARS-CoV-2 infection associated cell entry proteins ACE2, CD147, PPIA, and PPIB as potential prognostic and infection biomarkers in neuroblastoma

B Bergsneider, E Bailey, Y Ahmed, N Gogineni… - 2024 - authorea.com
Introduction: Although most children experience minor symptoms from SARS-CoV-2
infection, some develop complications including MIS-C. Neuroblastoma patients may be at …