Analytical characterization of liposomes and other lipid nanoparticles for drug delivery
Y Fan, M Marioli, K Zhang - Journal of pharmaceutical and biomedical …, 2021 - Elsevier
Lipid nanoparticles, especially liposomes and lipid/nucleic acid complexed nanoparticles
have shown great success in the pharmaceutical industry. Their success is attributed to …
have shown great success in the pharmaceutical industry. Their success is attributed to …
Ion mobility mass spectrometry in the omics era: Challenges and opportunities for metabolomics and lipidomics
G Paglia, AJ Smith, G Astarita - Mass Spectrometry Reviews, 2022 - Wiley Online Library
Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …
A cyclic ion mobility-mass spectrometry system
K Giles, J Ujma, J Wildgoose, S Pringle… - Analytical …, 2019 - ACS Publications
Improvements in the performance and availability of commercial instrumentation have made
ion mobility-mass spectrometry (IM-MS) an increasingly popular approach for the structural …
ion mobility-mass spectrometry (IM-MS) an increasingly popular approach for the structural …
Recurrent topics in mass spectrometry-based metabolomics and lipidomics—standardization, coverage, and throughput
We have come a long way in the last years of developing analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …
Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts
CG Vasilopoulou, K Sulek, AD Brunner… - Nature …, 2020 - nature.com
A comprehensive characterization of the lipidome from limited starting material remains very
challenging. Here we report a high-sensitivity lipidomics workflow based on nanoflow liquid …
challenging. Here we report a high-sensitivity lipidomics workflow based on nanoflow liquid …
Deep-profiling of phospholipidome via rapid orthogonal separations and isomer-resolved mass spectrometry
A lipidome comprises thousands of lipid species, many of which are isomers and isobars.
Liquid chromatography-tandem mass spectrometry (LC-MS/MS), although widely used for …
Liquid chromatography-tandem mass spectrometry (LC-MS/MS), although widely used for …
High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations
Mass spectrometry-based biomolecular analyses have become permanent fixtures of
academic, industrial, and clinical research settings. The rise in utilization of mass …
academic, industrial, and clinical research settings. The rise in utilization of mass …
High-performance molecular imaging with MALDI trapped ion-mobility time-of-flight (timsTOF) mass spectrometry
Imaging mass spectrometry (IMS) enables the spatially targeted molecular assessment of
biological tissues at cellular resolutions. New developments and technologies are essential …
biological tissues at cellular resolutions. New developments and technologies are essential …
Four-dimensional trapped ion mobility spectrometry lipidomics for high throughput clinical profiling of human blood samples
R Lerner, D Baker, C Schwitter, S Neuhaus… - Nature …, 2023 - nature.com
Lipidomics encompassing automated lipid extraction, a four-dimensional (4D) feature
selection strategy for confident lipid annotation as well as reproducible and cross-validated …
selection strategy for confident lipid annotation as well as reproducible and cross-validated …
Recent advances in differentiation of isomers by ion mobility mass spectrometry
Differentiation of isomers is an important analytical task in many fields, eg, chemistry,
biology, pharmaceutical science, medicine, environmental science, food science. Ion …
biology, pharmaceutical science, medicine, environmental science, food science. Ion …