Computational modeling of cardiac hemodynamics: current status and future outlook

R Mittal, JH Seo, V Vedula, YJ Choi, H Liu… - Journal of …, 2016 - Elsevier
The proliferation of four-dimensional imaging technologies, increasing computational
speeds, improved simulation algorithms, and the widespread availability of powerful …

Heart blood flow simulation: a perspective review

SN Doost, D Ghista, B Su, L Zhong… - Biomedical engineering …, 2016 - Springer
Cardiovascular disease (CVD), the leading cause of death today, incorporates a wide range
of cardiovascular system malfunctions that affect heart functionality. It is believed that the …

Image-based large-eddy simulation in a realistic left heart

C Chnafa, S Mendez, F Nicoud - Computers & Fluids, 2014 - Elsevier
A numerical framework allowing insight in fluid dynamics inside patient-specific human
hearts is presented. The heart cavities and their wall dynamics are extracted from medical …

Hemodynamics of the heart's left atrium based on a variational multiscale-LES numerical method

A Zingaro, F Menghini, A Quarteroni - European Journal of Mechanics-B …, 2021 - Elsevier
In this paper, we investigate the haemodynamics of a left atrium (LA) by proposing a
computational model suitable to provide physically meaningful fluid dynamics indications …

Impact of atrial fibrillation on left atrium haemodynamics: A computational fluid dynamics study

M Corti, A Zingaro, AM Quarteroni - Computers in Biology and Medicine, 2022 - Elsevier
We analyse the haemodynamics of the left atrium, highlighting differences between healthy
individuals and patients affected by atrial fibrillation. The computational study is based on …

[HTML][HTML] An electromechanics-driven fluid dynamics model for the simulation of the whole human heart

A Zingaro, M Bucelli, R Piersanti, F Regazzoni… - Journal of …, 2024 - Elsevier
We introduce a multiphysics and geometric multiscale computational model, suitable to
describe the hemodynamics of the whole human heart, driven by a four-chamber …

A geometric multiscale model for the numerical simulation of blood flow in the human left heart

A Zingaro, I Fumagalli, L Dede, M Fedele… - arXiv preprint arXiv …, 2021 - arxiv.org
We present a new computational model for the numerical simulation of blood flow in the
human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian …

[HTML][HTML] Effect of the mitral valve on diastolic flow patterns

JH Seo, V Vedula, T Abraham, AC Lardo, F Dawoud… - Physics of …, 2014 - pubs.aip.org
The leaflets of the mitral valve interact with the mitral jet and significantly impact diastolic
flow patterns, but the effect of mitral valve morphology and kinematics on diastolic flow and …

The numerical analysis of non-Newtonian blood flow in human patient-specific left ventricle

SN Doost, L Zhong, B Su, YS Morsi - Computer methods and programs in …, 2016 - Elsevier
Recently, various non-invasive tools such as the magnetic resonance image (MRI),
ultrasound imaging (USI), computed tomography (CT), and the computational fluid dynamics …

Effect of trabeculae and papillary muscles on the hemodynamics of the left ventricle

V Vedula, JH Seo, AC Lardo, R Mittal - Theoretical and Computational …, 2016 - Springer
The impact of surface trabeculae and papillary muscles on the hemodynamics of the left
ventricle (LV) is investigated using numerical simulations. Simulations of ventricular flow are …