The promise of engineering specific cell types from stem cells and rebuilding damaged or
diseased tissues has fascinated stem cell researchers and clinicians over last few decades …

Traumatic spinal cord injury (SCI) is a leading cause of lifelong disabilities. Permanent
sensory, motor and autonomic impairments after SCI are substantially attributed to …

Nanoneuromedicine investigates nanotechnology to target the brain and treat neurological
diseases. In this work, we biofabricated heterocellular spheroids comprising human brain …

For the past century, research on neurological disorders has largely focused on the most
prominently affected cell types–the neurons. However, with increasing knowledge of the …

All breast cancers are assessed for levels of human epidermal growth factor receptor 2
(HER2). Fluorescence in situ hybridization (FISH) and immunohistochemistry are currently …

Addictive stimulant drugs, such as cocaine, are known to increase the risk of exposure to
HIV-1 infection and hence predispose towards the development of AIDS. Previous findings …

Background Culturing primary cortical neurons is an essential neuroscience technique.
However, most cultures are derived from rodent brains and standard protocols for human …

Neurodevelopmental disorders (NDs) are impairments that affect the development and
growth of the brain and the central nervous system during embryonic and early postnatal life …

HIV‐1 infected individuals are at high risk of developing HIV‐associated neurocognitive
disorders (HAND) as HIV infection leads to neuronal injury and synaptic loss in the central …

Methods: We compared mtDNA or nDNA (nuclear DNA) damage in human cortical neurons
and PBMC cells. Primary neuronal cultures were incubated with conditioned media from HIV …