Thrombosis reflects an imbalance between procoagulant and anticoagulant mechanisms. In
some cases, thrombotic lesions are precipitated by gross changes in blood flow, vascular …

Nitrix oxide (NO) is a labile radical gas that is widely acclaimed as one of the most important
molecules in biology. Through covalent modifications of target proteins and redox reactions …

Vascular cell adhesion molecule-1 (VCAM-1) is a protein expressed on the surface of
activated endothelial cells and expressed in early atherosclerosis. Because part of the …

Renal and systemic nitric oxide synthesis in rats with renal mass reduction. In rats
undergoing renal mass reduction (RMR) oral supplementation with the nitric oxide (NO) …

Nitric oxide (NO) is released by the endothelium preventing platelet adhesion to the vessel
wall. When released by platelets, NO inhibits further recruitment of platelets to a growing …

Endothelial injury is the central factor in the events leading to thrombotic microangiopathy
(TMA); however, the mechanisms involved are not fully understood. Here we investigate the …

Background. Accelerated atherosclerosis is the major cause of mortality in patients on
chronic haemodialysis (HD). Increased oxidative stress might be the major factor leading to …

Propionyl-L-carnitine prevents renal function deterioration due to ischemia/reperfusion.
Background Ischemia-reperfusion injury after organ transplantation is a major cause of …

Longevity phenotype in humans results from the influence of environmental and genetic
factors. Few gene polymorphisms have been identified so far with a modest effect on …

ВазорелаÍсирующее свойство эндотелиального оÍсида азота (NО) отÍрыто в 1980 г., а в
1998 г. за проведенные исследования R. Furchgott, L. Ignarro и F. Murad были …