Artificial Intelligence in Oncology: Current Landscape, Challenges, and Future Directions

W Lotter, MJ Hassett, N Schultz, KL Kehl, EM Van Allen… - Cancer Discovery, 2024 - AACR
Artificial intelligence (AI) in oncology is advancing beyond algorithm development to
integration into clinical practice. This review describes the current state of the field, with a …

ChatGPT as an aid for pathological diagnosis of cancer

S Malik, S Zaheer - Pathology-Research and Practice, 2024 - Elsevier
Diagnostic workup of cancer patients is highly reliant on the science of pathology using
cytopathology, histopathology, and other ancillary techniques like immunohistochemistry …

Using generative AI to investigate medical imagery models and datasets

O Lang, D Yaya-Stupp, I Traynis, H Cole-Lewis… - …, 2024 - thelancet.com
Background AI models have shown promise in performing many medical imaging tasks.
However, our ability to explain what signals these models have learned is severely lacking …

[HTML][HTML] Artificial intelligence in colorectal cancer: from patient screening over tailoring treatment decisions to identification of novel biomarkers

NG Reitsam, JS Enke, K Vu Trung, B Märkl, JN Kather - Digestion, 2024 - karger.com
Background: Artificial intelligence (AI) is increasingly entering and transforming not only
medical research but also clinical practice. In the last 10 years, new AI methods have …

The SARIFA biomarker in the context of basic research of lipid-driven cancers

B Märkl, NG Reitsam, P Grochowski… - NPJ Precision …, 2024 - nature.com
SARIFA was very recently introduced as a histomorphological biomarker with strong
prognostic power for colorectal, gastric, prostate, and pancreatic cancer. It is characterized …

Novel biomarker SARIFA in colorectal cancer: highly prognostic, not genetically driven and histologic indicator of a distinct tumor biology

NG Reitsam, V Grozdanov, CML Löffler, HS Muti… - Cancer Gene …, 2024 - nature.com
Abstract SARIFA (Stroma AReactive Invasion Front Areas) has recently emerged as a
promising histopathological biomarker for colon and gastric cancer. To elucidate the …

Converging deep learning and human-observed tumor-adipocyte interaction as a biomarker in colorectal cancer

NG Reitsam, B Grosser, DF Steiner… - Communications …, 2024 - nature.com
Abstract Background Tumor-Adipose-Feature (TAF) as well as SARIFA (Stroma AReactive
Invasion Front Areas) are two histologic features/biomarkers linking tumor-associated …

The Concept of Stroma AReactive Invasion Front Areas (SARIFA) as a new prognostic biomarker for lipid-driven cancers holds true in pancreatic ductal …

P Grochowski, B Grosser, F Sommer, A Probst… - BMC cancer, 2024 - Springer
Background Pancreatic ductal adenocarcinoma (PDAC) is a 'difficult-to-treat'entity. To
forecast its prognosis, we introduced a new biomarker, SARIFA (stroma areactive invasion …

Artificial intelligence applications in histopathology

CD Bahadir, M Omar, J Rosenthal… - Nature Reviews …, 2024 - nature.com
Histopathology is a vital diagnostic discipline in medicine, fundamental to our
understanding, detection, assessment and treatment of conditions such as cancer, dementia …

Paving the path toward multi-omics approaches in the diagnostic challenges faced in thyroid pathology

I Piga, V L'Imperio, G Capitoli, V Denti… - Expert Review of …, 2023 - Taylor & Francis
Introduction Despite advancements in diagnostic methods, the classification of
indeterminate thyroid nodules still poses diagnostic challenges not only in pre-surgical …