Klebsiella pneumoniae infection biology: living to counteract host defences
JA Bengoechea, J Sa Pessoa - FEMS microbiology reviews, 2019 - academic.oup.com
Klebsiella species cause a wide range of diseases including pneumonia, urinary tract
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …
Klebsiella pneumoniae: going on the offense with a strong defense
MK Paczosa, J Mecsas - Microbiology and molecular biology …, 2016 - Am Soc Microbiol
Klebsiella pneumoniae causes a wide range of infections, including pneumonias, urinary
tract infections, bacteremias, and liver abscesses. Historically, K. pneumoniae has caused …
tract infections, bacteremias, and liver abscesses. Historically, K. pneumoniae has caused …
Molecular Pathogenesis of Klebsiella Pneumoniae
B Li, Y Zhao, C Liu, Z Chen, D Zhou - Future microbiology, 2014 - Taylor & Francis
Typical Klebsiella pneumoniae is an opportunistic pathogen, which mostly affects those with
weakened immune systems and tends to cause nosocomial infections. A subset of …
weakened immune systems and tends to cause nosocomial infections. A subset of …
The making of hypervirulent Klebsiella pneumoniae
P Dai, D Hu - Journal of Clinical Laboratory Analysis, 2022 - Wiley Online Library
Klebsiella pneumoniae is a notorious bacterium in clinical practice. Virulence, carbapenem‐
resistance and their convergence among K. pneumoniae are extensively discussed in this …
resistance and their convergence among K. pneumoniae are extensively discussed in this …
Modeling Klebsiella pneumoniae pathogenesis by infection of the wax moth Galleria mellonella
The implementation of infection models that approximate human disease is essential for
understanding pathogenesis at the molecular level and for testing new therapies before they …
understanding pathogenesis at the molecular level and for testing new therapies before they …
Klebsiella pneumoniae: Prevalence, Reservoirs, Antimicrobial Resistance, Pathogenicity, and Infection: A Hitherto Unrecognized Zoonotic Bacterium
Y Hu, J Anes, S Devineau, S Fanning - Foodborne pathogens and …, 2021 - liebertpub.com
Klebsiella pneumoniae is considered an opportunistic pathogen, constituting an ongoing
health concern for immunocompromised patients, the elderly, and neonates. Reports on the …
health concern for immunocompromised patients, the elderly, and neonates. Reports on the …
Clinical Implications of Genomic Adaptation and Evolution of Carbapenem-Resistant Klebsiella pneumoniae
A Gomez-Simmonds… - The Journal of infectious …, 2017 - academic.oup.com
Klebsiella pneumoniae poses a major challenge to healthcare worldwide as an important
cause of multidrug-resistant infections. Nosocomial clones, including epidemic sequence …
cause of multidrug-resistant infections. Nosocomial clones, including epidemic sequence …
Deciphering tissue-induced Klebsiella pneumoniae lipid A structure
E Llobet, V Martínez-Moliner… - Proceedings of the …, 2015 - National Acad Sciences
The outcome of an infection depends on host recognition of the pathogen, hence leading to
the activation of signaling pathways controlling defense responses. A long-held belief is that …
the activation of signaling pathways controlling defense responses. A long-held belief is that …
PRR-signaling pathways: learning from microbial tactics
G Sellge, TA Kufer - Seminars in immunology, 2015 - Elsevier
Recognition of bacterial pathogens by the mammalian host relies on the induction of early
innate immune responses initiated by the activation of pattern-recognition receptors (PRRs) …
innate immune responses initiated by the activation of pattern-recognition receptors (PRRs) …
A trans-kingdom T6SS effector induces the fragmentation of the mitochondrial network and activates innate immune receptor NLRX1 to promote infection
J Sá-Pessoa, S López-Montesino… - Nature …, 2023 - nature.com
Bacteria can inhibit the growth of other bacteria by injecting effectors using a type VI
secretion system (T6SS). T6SS effectors can also be injected into eukaryotic cells to facilitate …
secretion system (T6SS). T6SS effectors can also be injected into eukaryotic cells to facilitate …