The fight against poliovirus is not over
Poliovirus (PV), the virus that causes both acute poliomyelitis and post-polio syndrome, is
classified within the Enterovirus C species, and there are three wild PV serotypes: WPV1 …
classified within the Enterovirus C species, and there are three wild PV serotypes: WPV1 …
[HTML][HTML] Vaccine derived poliovirus (VDPV)
Poliomyelitis is caused by Poliovirus, a member of a large group of enteroviruses. Vaccine-
derived polioviruses (VDPVs) stem from mutated live poliovirus, which is contained in the …
derived polioviruses (VDPVs) stem from mutated live poliovirus, which is contained in the …
Immunogenicity of novel oral poliovirus vaccine type 2 administered concomitantly with bivalent oral poliovirus vaccine: an open-label, non-inferiority, randomised …
AL Wilkinson, K Zaman, M Hoque… - The Lancet Infectious …, 2023 - thelancet.com
Background Novel oral poliovirus vaccine type 2 (nOPV2) was developed by modifying the
Sabin strain to increase genetic stability and reduce risk of seeding new circulating vaccine …
Sabin strain to increase genetic stability and reduce risk of seeding new circulating vaccine …
Effectiveness of poliovirus vaccines against circulating vaccine-derived type 2 poliomyelitis in Nigeria between 2017 and 2022: a case-control study
LV Cooper, TB Erbeto, AA Danzomo… - The Lancet Infectious …, 2024 - thelancet.com
Summary Background Between 2018 and 2022, Nigeria experienced continuous
transmission of circulating vaccine-derived type 2 poliovirus (cVDPV2), with 526 cases of …
transmission of circulating vaccine-derived type 2 poliovirus (cVDPV2), with 526 cases of …
Safety of the novel oral poliovirus vaccine type 2 (nOPV2) in infants and young children aged 1 to< 5 years and lot-to-lot consistency of the immune response to …
M Ochoge, AC Futa, A Umesi, L Affleck, L Kotei… - The Lancet, 2024 - thelancet.com
Background Novel oral poliovirus vaccine type 2 (nOPV2) has been engineered to improve
the genetic stability of Sabin oral poliovirus vaccine (OPV) and reduce the emergence of …
the genetic stability of Sabin oral poliovirus vaccine (OPV) and reduce the emergence of …
[HTML][HTML] Notes from the field: circulating vaccine-derived poliovirus type 2 emergences linked to novel oral poliovirus vaccine type 2 use—six African countries, 2021 …
E Davlantes - MMWR. Morbidity and Mortality Weekly Report, 2023 - cdc.gov
Circulating vaccine-derived poliovirus (cVDPV) outbreaks can occur when oral poliovirus
vaccine strains (most often, Sabin monovalent oral poliovirus vaccine type 2 [mOPV2]) …
vaccine strains (most often, Sabin monovalent oral poliovirus vaccine type 2 [mOPV2]) …
Safety and immunogenicity of shorter interval schedules of the novel oral poliovirus vaccine type 2 in infants: a phase 3, randomised, controlled, non-inferiority study in …
LR Mejía, LP Méndez, AS Bandyopadhyay… - The Lancet Infectious …, 2024 - thelancet.com
Background The novel oral poliovirus vaccine type 2 (nOPV2) is now authorised by a WHO
emergency use listing and widely distributed to interrupt outbreaks of circulating vaccine …
emergency use listing and widely distributed to interrupt outbreaks of circulating vaccine …
Threat of resurgence or hope for global eradication of poliovirus?
CY Kim, B Piamonte, R Allen… - Current Opinion in …, 2023 - journals.lww.com
Threat of resurgence or hope for global eradication of polio... : Current Opinion in Neurology
Threat of resurgence or hope for global eradication of poliovirus? : Current Opinion in …
Threat of resurgence or hope for global eradication of poliovirus? : Current Opinion in …
First Africa-based clinical trial for novel type 2 oral poliovirus vaccine
LV Cooper, IM Blake - The Lancet, 2024 - thelancet.com
The Global Polio Eradication Initiative owes much of its success in vastly reducing wild
poliovirus transmission globally to the use of live-attenuated Sabin oral poliovirus vaccine …
poliovirus transmission globally to the use of live-attenuated Sabin oral poliovirus vaccine …
Identifying and reducing risks of neurological complications associated with vaccination
L Handunnetthi, MN Ramasamy, L Turtle… - Nature Reviews …, 2024 - nature.com
Vaccines protect against many infectious diseases, including some that can directly or
indirectly cause nervous system damage. Serious neurological consequences of …
indirectly cause nervous system damage. Serious neurological consequences of …