Epithelial–mesenchymal transition and its transcription factors

P Debnath, RS Huirem, P Dutta… - Bioscience …, 2022 - portlandpress.com
Epithelial–mesenchymal transition or EMT is an extremely dynamic process involved in
conversion of epithelial cells into mesenchymal cells, stimulated by an ensemble of …

The role of immune modulatory cytokines in the tumor microenvironments of head and neck squamous cell carcinomas

N Kondoh, M Mizuno-Kamiya - Cancers, 2022 - mdpi.com
Simple Summary Malignant phenotypes of head and neck squamous cell carcinomas
(HNSCCs) are regulated by the pro-and anti-tumoral activities of immune modulatory …

DDX20: A Multifunctional Complex Protein

L He, J Yang, Y Hao, X Yang, X Shi, D Zhang, D Zhao… - Molecules, 2023 - mdpi.com
DEAD-box decapping enzyme 20 (DDX20) is a putative RNA-decapping enzyme that can
be identified by the conserved motif Asp–Glu–Ala–Asp (DEAD). Cellular processes involve …

Allyl isothiocyanate suppresses the proliferation in oral squamous cell carcinoma via mediating the KDM8/CCNA1 axis

CC Hsieh, CY Yang, B Peng, SL Ho, CH Tsao, CK Lin… - Biomedicines, 2023 - mdpi.com
The dysregulated expression of cyclin genes can lead to the uncontrolled proliferation of
cancer cells. Histone demethylase Jumonji-C domain-containing protein 5 (KDM8, JMJD5) …

Strategic approaches in oral squamous cell carcinoma diagnostics using liquid biopsy

DF Kinane, J Gabert, G Xynopoulos… - Periodontology …, 2024 - Wiley Online Library
Liquid biopsy is a noninvasive diagnostic technique used for monitoring cancer utilizing
specific genetic biomarkers present in bodily fluids, such as blood, saliva, or urine. These …

Propofol induces apoptosis and ameliorates 5-fluorouracil resistance in OSCC cells by reducing the expression and secretion of amphiregulin

KS Yang, PC Che, MJ Hsieh… - Molecular …, 2022 - spandidos-publications.com
Among the different types of oral cancer,> 90% of cases are oral squamous cell carcinoma
(OSCC). 5-fluorouracil (5-FU) is a commonly used treatment for OSCC, but cells typically …

[HTML][HTML] Identifying Key Genes Involved in Axillary Lymph Node Metastasis in Breast Cancer Using Advanced RNA-Seq Analysis: A Methodological Approach with …

M Rezapour, R Wesolowski, MN Gurcan - International journal of …, 2024 - mdpi.com
Our study aims to address the methodological challenges frequently encountered in RNA-
Seq data analysis within cancer studies. Specifically, it enhances the identification of key …

DDX27 regulates oral squamous cell carcinoma development through targeting CSE1L

G Li, R Li, W Wang, M Sun, X Wang - Life Sciences, 2024 - Elsevier
The headings aims DEAD-box helicase 27 (DDX27), a member of the DEAD-Box nucleic
acid helicase family, holds an elusive role in oral squamous cell carcinoma (OSCC). This …

Angiopoietin‐like 4 is upregulated by amphiregulin and activates cell proliferation and migration through p38 kinase in head and neck squamous cell carcinoma

A Kumar, E Asiedu, E Hefni… - Journal of Oral …, 2024 - Wiley Online Library
Background Angiopoietin‐like 4 is a molecular hallmark that correlates with the growth and
metastasis of head and neck squamous cell carcinoma, one of the most prevalent cancers …

Development of a novel head and neck squamous cell carcinoma prognostic signature by bulk/single‐cell sequencing data integration

Y Dai, J Li, R Huang, Q Yao, Y Shi, S Guo… - Oral …, 2024 - Wiley Online Library
Background Identifying cell subpopulations conferring unfavorable prognosis in cancer
holds clinical significance. Here, we sought to identify prognostic cell subsets and develop a …