The incidence of allergic diseases continues to rise. Cross-sectional and longitudinal
studies have indicated that allergic diseases occur in a time-based order: from atopic …

Progress in understanding of the mechanisms underlying chronic inflammatory skin
disorders, such as atopic dermatitis and psoriasis vulgaris, has led to new treatment options …

Avermectins are a group of drugs that occurs naturally as a product of fermenting
Streptomyces avermitilis, an actinomycetes, isolated from the soil. Eight different structures …

The skin provides both a physical barrier and an immunologic barrier to external threats. The
protective machinery of the skin has evolved to provide situation-specific responses to …

Autoimmune skin diseases are characterized by significant local and systemic inflammation
that is largely mediated by the Janus kinase (JAK)–signal transducer and activator of …

Atopic dermatitis often precedes the development of other atopic diseases. The atopic march
describes this temporal relationship in the natural history of atopic diseases. Although the …

Innate lymphoid cells (ILCs) are a recently identified family of heterogeneous immune cells
that can be divided into three groups based on their differential developmental requirements …

Background: Vitamin D is a secosteroid, which was initially known for its skeletal role;
however, in recent years, its functions in different organs have been increasingly …

Atopic dermatitis (AD) is a recurrent, chronic, and inflammatory skin disease, which
processes with severe itchiness. It often coexists with different atopic diseases. The number …

Mast cell (MC) mediator release after crosslinking of surface-bound IgE antibody by ingested
antigen underlies food allergy. However, IgE antibodies are not uniformly associated with …