Hydrogels are crosslinked polymer chains with three-dimensional (3D) network structures,
which can absorb relatively large amounts of fluid. Because of the high water content, soft …

Human struggle against the deadly disease conditions is continued since ages. The
contribution of science and technology in fighting against these diseases cannot be ignored …

Cilostazol (CLZ) is an antiplatelet agent with limited solubility (∼ 6 μg/ml at 25° C), poor
absorption and low oral bioavailability. In this study, solid lipid nanoparticles (SLNs) were …

Herein, we reported novel docetaxel-decorated solid lipid nanoparticle (DCT-SLN)-loaded
dual thermoreversible system (DCT-DRTS) for intramuscular administration with reduced …

The rectal route is an effective route for the local and systemic delivery of active
pharmaceutical ingredients. The environment of the rectum is relatively constant with low …

Topical delivery is preferable over systemic delivery for cutaneous leishmaniasis, because
of its easy administration, reduced systemic adverse effects and low cost. Nitazoxanide …

Abstract Dexibuprofen (DBPN), a non-steroidal anti-inflammatory drug (NSAID), exhibit its
action by inhibiting COX enzymes. It belongs to BCS class Ⅱ drugs, owing to its poor …

Colorectal cancer (CRC) is a usual digestive tract malignancy and the third main cause of
cancer death around the world, with a high occurrence rate and mortality rate. Conventional …

Revaprazan (REV), a novel reversible Proton Pump Inhibitor (PPI) used to treat peptic
ulcers, faces challenges in therapeutic efficacy due to its poor dissolution properties and a …

Migraine is a progressive neurological condition often accompanied by nausea and
vomiting. Various drugs have recently been used in the treatment of migraine, including …