Cognitive decline in chronic diabetic patients is a less investigated topic. Diabetes and
obesity are among the modifiable risk factors for Alzheimer's disease (AD), the most …

Obesity and diabetes are the most common metabolic disorders, which are strongly related
to Alzheimer's disease (AD) in aging. Diabetes and obesity can lead to the accumulation of …

Diabetes often leads to a number of complications involving brain function, including
cognitive decline and depression. In addition, depression is a risk factor for developing …

The aim of the present study was to analyze the action of metformin on short-term memory,
glial cell activation and neuroinflammation caused by experimental diabetic encephalopathy …

It is now well established that the mammalian brain has the capacity to produce new
neurons into adulthood. One such region that provides the proper milieu to sustain …

Overnutrition and modern diets containing high proportions of saturated fat are among the
major factors contributing to a low-grade state of inflammation, hyperglycemia and …

High-caloric diet and physical inactivity predispose individuals to obesity and diabetes,
which are risk factors of hippocampal neurodegeneration and cognitive deficits. Along with …

According to World Health Organization estimates, type 2 diabetes (T2D) is an epidemic
(particularly in under development countries) and a socio-economic challenge. This is even …

Type 1 diabetes (T1D) is accompanied by a “diabetic encephalopathy” including
hypersensitivity to stress, increased risk of stroke, dementia and cognitive impairment. In …

From epidemiological studies it is known that diabetes patients display increased risk of
developing dementia. Moreover, cognitive impairment and Alzheimer's disease (AD) are …