[HTML][HTML] Quitting smoking at or around diagnosis improves the overall survival of lung cancer patients: a systematic review and meta-analysis

S Caini, M Del Riccio, V Vettori, V Scotti… - Journal of Thoracic …, 2022 - Elsevier
Introduction Lung cancer (LC) remains a disease with poor prognosis despite recent
advances in treatments. Here, we aimed at summarizing the current scientific evidence on …

[HTML][HTML] Triple-negative breast cancer: current understanding and future therapeutic breakthrough targeting cancer stemness

KL Lee, YC Kuo, YS Ho, YH Huang - Cancers, 2019 - mdpi.com
Triple-negative breast cancer (TNBC) is cancer that tested as negative for estrogen
receptors (ER), progesterone receptors (PR), and excess human epidermal growth factor …

[HTML][HTML] Nicotine promotes breast cancer metastasis by stimulating N2 neutrophils and generating pre-metastatic niche in lung

A Tyagi, S Sharma, K Wu, SY Wu, F Xing, Y Liu… - Nature …, 2021 - nature.com
Smoking has a profound impact on tumor immunity, and nicotine, which is the major
addictive component of smoke, is known to promote tumor progression despite being a non …

[PDF][PDF] Particle size, penetration rate and effects of smoke and smokeless tobacco products–an invitro analysis

JVM Antony, P Ramani, A Ramasubramanian… - Heliyon, 2021 - cell.com
Utilization of tobacco products is a global epidemic that causes a health threat among the
adolescents and adults of the world. If the current pattern perpetuates, it is estimated to …

Connections of nicotine to cancer

SA Grando - Nature Reviews Cancer, 2014 - nature.com
This Opinion article discusses emerging evidence of direct contributions of nicotine to
cancer onset and growth. The list of cancers reportedly connected to nicotine is expanding …

Nicotine-mediated cell proliferation and tumor progression in smoking-related cancers

C Schaal, SP Chellappan - Molecular Cancer Research, 2014 - AACR
Tobacco smoke contains multiple classes of established carcinogens including benzo (a)
pyrenes, polycyclic aromatic hydrocarbons, and tobacco-specific nitrosamines. Most of these …

Cytotoxicity evaluation of electronic cigarette vapor extract on cultured mammalian fibroblasts (ClearStream-LIFE): comparison with tobacco cigarette smoke extract

G Romagna, E Allifranchini, E Bocchietto… - Inhalation …, 2013 - Taylor & Francis
Abstract Context: Electronic cigarettes (ECs) are used as alternatives to smoking; however,
data on their cytotoxic potential are scarce. Objective: To evaluate the cytotoxic potential of …

[HTML][HTML] Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer

CM Schaal, N Bora-Singhal, DM Kumar… - Molecular cancer, 2018 - Springer
Background Lung cancer is the leading cause of cancer related deaths and its incidence is
highly correlated with cigarette smoking. Nicotine, the addictive component of tobacco …

[HTML][HTML] Nicotine: carcinogenicity and effects on response to cancer treatment–a review

T Sanner, TK Grimsrud - Frontiers in oncology, 2015 - frontiersin.org
Tobacco use is considered the single most important man-made cause of cancer that can be
avoided. The evidence that nicotine is involved in cancer development is reviewed and …

Therapeutic potential of α7 nicotinic acetylcholine receptors

D Bertrand, CHL Lee, D Flood, F Marger… - Pharmacological …, 2015 - ASPET
Progress in the fields of neuroscience and molecular biology has identified the forebrain
cholinergic system as being important in many higher order brain functions. Further analysis …