[HTML][HTML] GPI-AP: unraveling a new class of malignancy mediators and potential immunotherapy targets
NH Hussein, NS Amin, HM El Tayebi - Frontiers in Oncology, 2020 - frontiersin.org
With millions of cases diagnosed annually and high economic burden to cover expensive
costs, cancer is one of the most difficult diseases to treat due to late diagnosis and severe …
costs, cancer is one of the most difficult diseases to treat due to late diagnosis and severe …
A soluble, minimalistic glycosylphosphatidylinositol transamidase (GPI-T) retains transamidation activity
Glycosylphosphatidylinositol (GPI) anchoring of proteins is a eukaryotic, post-translational
modification catalyzed by GPI transamidase (GPI-T). The Saccharomyces cerevisiae GPI-T …
modification catalyzed by GPI transamidase (GPI-T). The Saccharomyces cerevisiae GPI-T …
[HTML][HTML] Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer
CD24 is frequently overexpressed in ovarian cancer and promotes immune evasion by
interacting with its receptor Siglec10, present on tumor-associated macrophages, providing …
interacting with its receptor Siglec10, present on tumor-associated macrophages, providing …
Expanding the Phenotypic Spectrum of GPI Anchoring Deficiency Due to Biallelic Variants in GPAA1
Background and Objectives To expand the clinical knowledge of GPAA 1-related
glycosylphosphatidylinositol (GPI) deficiency. Methods An international case series of 7 …
glycosylphosphatidylinositol (GPI) deficiency. Methods An international case series of 7 …
Cellular heterogeneity and immune microenvironment revealed by single-cell transcriptome in venous malformation and cavernous venous malformation
Y Li, J Yang, Y Huang, S Ge, X Song, R Jia… - Journal of Molecular and …, 2022 - Elsevier
Venous malformation (VM) and cavernous venous malformation (CVM) are two types of
vascular malformations. Even if the two diseases are similar in appearance and imaging, the …
vascular malformations. Even if the two diseases are similar in appearance and imaging, the …
Structure and Function of the Glycosylphosphatidylinositol Transamidase, a Transmembrane Complex Catalyzing GPI Anchoring of Proteins
D Li - Macromolecular Protein Complexes V: Structure and …, 2024 - Springer
Glycosylphosphatidylinositol (GPI) anchoring of proteins is a ubiquitous posttranslational
modification in eukaryotic cells. GPI-anchored proteins (GPI-APs) play critical roles in …
modification in eukaryotic cells. GPI-anchored proteins (GPI-APs) play critical roles in …
[HTML][HTML] In search of excellence: from a small clinical unit to an internationally recognized center for orbital diseases research and surgery at the Department of …
X Song, H Zhou, Y Wang, M Yang, S Fang, Y Li… - Asia-Pacific Journal of …, 2021 - Elsevier
“Where there is a will, there is a way.” It is never easy to make progress and development
but with full dedication and firm commitment, many aspirations can still be realized. We …
but with full dedication and firm commitment, many aspirations can still be realized. We …
[HTML][HTML] Comprehensive circular RNA expression profiling with associated ceRNA network in orbital venous malformation
J Yu, P Chai, Y Zhou, R Jia, Y Wang - Molecular Vision, 2022 - ncbi.nlm.nih.gov
Purpose Orbital venous malformation (OVM), the most common type of vascular
malformation in adults, has a great impact on both visual and cosmetic factors. Circular …
malformation in adults, has a great impact on both visual and cosmetic factors. Circular …
[HTML][HTML] A Novel Homozygous GPAA1 Variant in a Patient with a Glycosylphosphatidylinositol Biosynthesis Defect
P Fontana, A Budillon, D Simeone… - Genes, 2023 - mdpi.com
Glycosylphosphatidylinositol biosynthesis defect 15 is a rare autosomal recessive disorder
due to biallelic loss of function of GPAA1. At the moment, less than twenty patients have …
due to biallelic loss of function of GPAA1. At the moment, less than twenty patients have …