Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …

Arachidonic acid (AA) metabolism is critical in the initiation and resolution of inflammation.
Prostaglandin E2 (PGE2) and leukotriene B4/D4/E4 (LTB4/LD4/LTE4), derived from AA, are …

Mesenchymal stem cells (MSCs) are speculated to act at macrophage-injury interfaces to
mediate efficient repair. To explore this facet in-depth this study evaluates the influence of …

Oncolytic viruses (OVs) infect, multiply, and finally remove tumor cells selectively, causing no
damage to normal cells in the process. Because of their specific features, such as, the ability …

Hepatic fibrosis/cirrhosis is a significant health burden worldwide, resulting in liver failure or
hepatocellular carcinoma (HCC) and accounting for many deaths each year. The …

The availability of multiple disease-modifying medications with regulatory approval to treat
multiple sclerosis illustrates the substantial progress made in therapy of the disease …

Psoriasis is a common, chronic immune-mediated systemic disease that had no effective
and durable treatment. Mesenchymal stem cells (MSCs) have immunomodulatory …

Abstract Background Mesenchymal stem cells (MSCs) are multipotent cells with broad
immunosuppressive capacities. Recently, it has been reported that MSCs can transfer …

Lipids are an essential constituent of the cell membrane of which polyunsaturated fatty acids
(PUFAs) are the most important component. Activation of phospholipase A2 (PLA2) induces …

Background Defective clearance of apoptotic cells (ACs) has been suggested to be involved
in the pathogenesis of systemic lupus erythematosus (SLE). Mesenchymal stem cells …