An insight into medicinal chemistry of anticancer quinoxalines

T Kaushal, G Srivastava, A Sharma, AS Negi - Bioorganic & Medicinal …, 2019 - Elsevier
Quinoxalines are benzopyrazines containing benzene and pyrazine rings fused together. In
the recent past, quinoxalines have attracted Medicinal Chemists considerably for their …

Sustainable approaches towards the synthesis of quinoxalines: An update

A Kumar, TM Dhameliya, K Sharma, KA Patel… - Journal of Molecular …, 2022 - Elsevier
Heterocycles and their derivatives have been inspiring medicinal chemists to device novel,
greener and efficient ways to synthesized them as the majority of drugs available in the …

Synthesis of pyrazines and quinoxalines via acceptorless dehydrogenative coupling routes catalyzed by manganese pincer complexes

P Daw, A Kumar, NA Espinosa-Jalapa… - ACS …, 2018 - ACS Publications
Base-metal catalyzed dehydrogenative self-coupling of 2-amino alcohols to selectively form
functionalized 2, 5-substituted pyrazine derivatives is presented. Also, 2-substituted …

Efficient synthesis of quinoxalines from 2-nitroanilines and vicinal diols via a ruthenium-catalyzed hydrogen transfer strategy

F Xie, M Zhang, H Jiang, M Chen, W Lv, A Zheng… - Green …, 2015 - pubs.rsc.org
Via a ruthenium-catalyzed hydrogen transfer strategy, we have demonstrated a one-pot
method for efficient synthesis of quinoxalines from 2-nitroanilines and biomass-derived …

An efficient synthetic route of quinoxalines from diols catalyzed by [RuCl2 (p-cymene)] 2/1, 4-bis (diphenylphosphino) butane

P Zeng, X Li, L Li, C Liang, J Zhang, T Peng - Journal of Organometallic …, 2023 - Elsevier
An efficient and convenient homogeneous catalytic system is developed from commercially
available Ru complex ([Ru (p-cymene) Cl 2] 2) and 1, 4-bis (diphenylphosphino) butane …

Iron‐catalyzed annulation of 1, 2‐diamines and diazodicarbonyls for diverse and polyfunctionalized quinoxalines, pyrazines, and benzoquinoxalines in water

RP Pandit, SH Kim, YR Lee - Advanced Synthesis & Catalysis, 2016 - Wiley Online Library
A novel and facile iron‐catalyzed tandem annulation of o‐phenylenediamines and
diazocarbonyls in water for the construction of polyfunctionalized quinoxalines has been …

One-step approach for the synthesis of functionalized quinoxalines mediated by T3P®–DMSO or T3P® via a tandem oxidation–condensation or condensation …

KB Harsha, KS Rangappa - RSC advances, 2016 - pubs.rsc.org
An easy and efficient propylphosphonic anhydride (T3P®)–DMSO or T3P® mediated
oxidation–condensation or condensation reaction for the synthesis of quinoxalines derived …

Iridium‐catalyzed carbenoid insertion of sulfoxonium ylides for synthesis of quinoxalines and β‐keto thioethers in water

Y Xu, X Huang, G Lv, R Lai, S Lv, J Li… - European Journal of …, 2020 - Wiley Online Library
Sulfoxonium ylides as safe carbene precursors are described for iridium‐catalyzed carbene
insertions and annulation, providing a facile and green approach to access a variety of …

Substrate‐Controlled Product Divergence in Iron (III)‐Catalyzed Reactions of Propargylic Alcohols: Easy Access to Spiro‐indenyl 1, 4‐Benzoxazines and 2‐(2, 2 …

S De, C Chowdhury - Chemistry–A European Journal, 2023 - Wiley Online Library
We report herein unprecedented cascade reactions of O‐propargyl‐N‐tosyl‐amino phenols
with 10 mol% FeCl3 in DCE at room temperature for 0.67–3 h to form spiro‐indenyl 1, 4 …

Recent developments in one-pot tandem oxidation process coupling reactions

V Jeena, RS Robinson - RSC Advances, 2014 - pubs.rsc.org
The tandem oxidation process (TOP) constitutes a novel approach to synthetic organic
chemistry. This procedure involves the oxidation of the alcohol to the aldehyde which is …