[HTML][HTML] Obesity, metabolic syndrome, and musculoskeletal disease: common inflammatory pathways suggest a central role for loss of muscle integrity
Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …
[HTML][HTML] The role of macrophages in osteoarthritis and cartilage repair
CL Wu, NS Harasymowicz, MA Klimak… - Osteoarthritis and …, 2020 - Elsevier
Osteoarthritis (OA) is a family of degenerative diseases affecting multiple joint tissues.
Despite the diverse etiology and pathogenesis of OA, increasing evidence suggests that …
Despite the diverse etiology and pathogenesis of OA, increasing evidence suggests that …
[HTML][HTML] Prevalence and mechanisms of skeletal muscle atrophy in metabolic conditions
L Jun, M Robinson, T Geetha, TL Broderick… - International Journal of …, 2023 - mdpi.com
Skeletal muscle atrophy is prevalent in a myriad of pathological conditions, such as
diabetes, denervation, long-term immobility, malnutrition, sarcopenia, obesity, Alzheimer's …
diabetes, denervation, long-term immobility, malnutrition, sarcopenia, obesity, Alzheimer's …
[HTML][HTML] Blood-brain barrier permeability following conventional photon radiotherapy–A systematic review and meta-analysis of clinical and preclinical studies
Z Odé, MPP Derieppe, L Groenink… - Clinical and translational …, 2022 - Elsevier
Radiotherapy (RT) is a cornerstone treatment strategy for brain tumours. Besides
cytotoxicity, RT can cause disruption of the blood–brain barrier (BBB), resulting in an …
cytotoxicity, RT can cause disruption of the blood–brain barrier (BBB), resulting in an …
Short and long-term effects of bisphenol S (BPS) exposure during pregnancy and lactation on plasma lipids, hormones, and behavior in rats
BS da Silva, CB Pietrobon, IM Bertasso, BP Lopes… - Environmental …, 2019 - Elsevier
Bisphenol S (BPS) has replaced bisphenol A (BPA), a known non-persistent endocrine
disrupting chemical, in several products. Considering that little is known regarding BPS …
disrupting chemical, in several products. Considering that little is known regarding BPS …
[HTML][HTML] Alterations in skeletal muscle morphology and mechanics in juvenile male Sprague Dawley rats exposed to a high-fat high-sucrose diet
Although once a health concern largely considered in adults, the obesity epidemic is now
prevalent in pediatric populations. While detrimental effects on skeletal muscle function have …
prevalent in pediatric populations. While detrimental effects on skeletal muscle function have …
Obesity impairs enthesis healing after rotator cuff repair in a rat model
Background: Being overweight or obese is associated with poor outcomes and an increased
risk of failure after rotator cuff (RC) surgery. However, the effect of obesity on enthesis …
risk of failure after rotator cuff (RC) surgery. However, the effect of obesity on enthesis …
Beneficial effects of metformin on muscle atrophy induced by obesity in rats
MM Hasan, SM Shalaby, J El‐Gendy… - Journal of cellular …, 2019 - Wiley Online Library
Aim A growing interest to understand the signaling pathways mediating obesity‐induced
muscle atrophy is given. Metformin (Met) was reported to possess positive effects on …
muscle atrophy is given. Metformin (Met) was reported to possess positive effects on …
Modifiability of residual force depression in single muscle fibers following uphill and downhill training in rats
Following active muscle shortening, steady‐state isometric force is less than a purely
isometric contraction at the same muscle length and level of activation; this is known as …
isometric contraction at the same muscle length and level of activation; this is known as …
[HTML][HTML] Effects of exercise and a high-fat, high-sucrose restriction diet on metabolic indicators, Nr4a3, and mitochondria-associated protein expression in the …
Background Exercise and high fat, high sucrose restriction diets are well known treatments
for obesity. The aim of this study was to measure the effects of those lifestyle interventions on …
for obesity. The aim of this study was to measure the effects of those lifestyle interventions on …