[HTML][HTML] Obesity, metabolic syndrome, and musculoskeletal disease: common inflammatory pathways suggest a central role for loss of muscle integrity

KH Collins, W Herzog, GZ MacDonald… - Frontiers in …, 2018 - frontiersin.org
Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …

[HTML][HTML] The role of macrophages in osteoarthritis and cartilage repair

CL Wu, NS Harasymowicz, MA Klimak… - Osteoarthritis and …, 2020 - Elsevier
Osteoarthritis (OA) is a family of degenerative diseases affecting multiple joint tissues.
Despite the diverse etiology and pathogenesis of OA, increasing evidence suggests that …

[HTML][HTML] Prevalence and mechanisms of skeletal muscle atrophy in metabolic conditions

L Jun, M Robinson, T Geetha, TL Broderick… - International Journal of …, 2023 - mdpi.com
Skeletal muscle atrophy is prevalent in a myriad of pathological conditions, such as
diabetes, denervation, long-term immobility, malnutrition, sarcopenia, obesity, Alzheimer's …

[HTML][HTML] Blood-brain barrier permeability following conventional photon radiotherapy–A systematic review and meta-analysis of clinical and preclinical studies

Z Odé, MPP Derieppe, L Groenink… - Clinical and translational …, 2022 - Elsevier
Radiotherapy (RT) is a cornerstone treatment strategy for brain tumours. Besides
cytotoxicity, RT can cause disruption of the blood–brain barrier (BBB), resulting in an …

Short and long-term effects of bisphenol S (BPS) exposure during pregnancy and lactation on plasma lipids, hormones, and behavior in rats

BS da Silva, CB Pietrobon, IM Bertasso, BP Lopes… - Environmental …, 2019 - Elsevier
Bisphenol S (BPS) has replaced bisphenol A (BPA), a known non-persistent endocrine
disrupting chemical, in several products. Considering that little is known regarding BPS …

[HTML][HTML] Alterations in skeletal muscle morphology and mechanics in juvenile male Sprague Dawley rats exposed to a high-fat high-sucrose diet

M Delgado-Bravo, DA Hart, RA Reimer, W Herzog - Scientific Reports, 2023 - nature.com
Although once a health concern largely considered in adults, the obesity epidemic is now
prevalent in pediatric populations. While detrimental effects on skeletal muscle function have …

Obesity impairs enthesis healing after rotator cuff repair in a rat model

SM Bolam, YE Park, S Konar… - … American Journal of …, 2021 - journals.sagepub.com
Background: Being overweight or obese is associated with poor outcomes and an increased
risk of failure after rotator cuff (RC) surgery. However, the effect of obesity on enthesis …

Beneficial effects of metformin on muscle atrophy induced by obesity in rats

MM Hasan, SM Shalaby, J El‐Gendy… - Journal of cellular …, 2019 - Wiley Online Library
Aim A growing interest to understand the signaling pathways mediating obesity‐induced
muscle atrophy is given. Metformin (Met) was reported to possess positive effects on …

Modifiability of residual force depression in single muscle fibers following uphill and downhill training in rats

P Mashouri, J Chen, AM Noonan… - Physiological …, 2021 - Wiley Online Library
Following active muscle shortening, steady‐state isometric force is less than a purely
isometric contraction at the same muscle length and level of activation; this is known as …

[HTML][HTML] Effects of exercise and a high-fat, high-sucrose restriction diet on metabolic indicators, Nr4a3, and mitochondria-associated protein expression in the …

JH Lee, D Zhang, SE Kwak, HE Shin… - Journal of Obesity & …, 2021 - ncbi.nlm.nih.gov
Background Exercise and high fat, high sucrose restriction diets are well known treatments
for obesity. The aim of this study was to measure the effects of those lifestyle interventions on …