Anticancer immune responses can be considered a desirable form of autoimmunity that may
be profoundly shaped by the microbiome. Here, we discuss evidence for the microbiome's …

Most pathogens enter the body through mucosal surfaces. Therefore, vaccination through
the mucosal route can greatly enhance the mucosal immune response. Vaccination via the …

Microfold cells (M cells) are specialized epithelial cells situated over Peyer's patches (PP)
and other organized mucosal lymphoid tissues that transport commensal bacteria and other …

Abundant evidence supports the notion that human intestinal plasma cells are largely
derived from B cells initially activated in gut-associated lymphoid tissue (GALT) …

Mucosal surfaces are continuously exposed to the external environment and therefore
represent the largest lymphoid organ of the body. In the mucosal immune system, gut …

Objective—Atherosclerosis is an inflammatory disease. Autoimmune responses to low-
density lipoproteins (LDL) contribute to its progression, whereas immunization with LDL may …

Infectious diseases continue to inflict a high global disease burden. The consensus is that
vaccination is the most effective option against infectious diseases. Oral vaccines have …

The INHAND Project (International Harmonization of Nomenclature and Diagnostic Criteria
for Lesions in Rats and Mice) is a joint initiative of the Societies of Toxicologic Pathology …

Alcaligenes faecalis is the predominant Gram‐negative bacterium inhabiting gut‐associated
lymphoid tissues, Peyer's patches. We previously reported that an A. faecalis …

To develop protective immune responses against mucosal pathogens, the delivery route
and adjuvants for vaccination are important. The host, however, strives to maintain mucosal …