Achieving zero extinction for land plants

RT Corlett - Trends in Plant Science, 2023 - cell.com
Despite the importance of plants for humans and the threats to their future, plant
conservation receives far less support compared with vertebrate conservation. Plants are …

Resistance to natural and synthetic gene drive systems

TAR Price, N Windbichler, RL Unckless… - Journal of …, 2020 - academic.oup.com
Scientists are rapidly developing synthetic gene drive elements intended for release into
natural populations. These are intended to control or eradicate disease vectors and pests, or …

Overriding Mendelian inheritance in Arabidopsis with a CRISPR toxin–antidote gene drive that impairs pollen germination

Y Liu, B Jiao, J Champer, W Qian - Nature Plants, 2024 - nature.com
Synthetic gene drives, inspired by natural selfish genetic elements and transmitted to
progeny at super-Mendelian (> 50%) frequencies, present transformative potential for …

Regulation of synthetic biology: developments under the convention on biological diversity and its protocols

F Keiper, A Atanassova - Frontiers in bioengineering and …, 2020 - frontiersin.org
The primary international forum deliberating the regulation of “synthetic biology” is the
Convention on Biological Diversity (CBD), along with its subsidiary agreements concerned …

Incorporating ecology into gene drive modelling

J Kim, KD Harris, IK Kim, S Shemesh… - Ecology …, 2023 - Wiley Online Library
Gene drive technology, in which fast‐spreading engineered drive alleles are introduced into
wild populations, represents a promising new tool in the fight against vector‐borne diseases …

Strong and tunable anti‐CRISPR/Cas activities in plants

C Calvache, M Vazquez‐Vilar, S Selma… - Plant biotechnology …, 2022 - Wiley Online Library
CRISPR/Cas has revolutionized genome engineering in plants. However, the use of anti‐
CRISPR proteins as tools to prevent CRISPR/Cas‐mediated gene editing and gene …

Gene drive: progress and prospects

N Wedell, TAR Price… - Proceedings of the …, 2019 - royalsocietypublishing.org
Gene drive is a naturally occurring phenomenon in which selfish genetic elements
manipulate gametogenesis and reproduction to increase their own transmission to the next …

Cleave and Rescue gamete killers create conditions for gene drive in plants

G Oberhofer, ML Johnson, T Ivy, I Antoshechkin… - Nature Plants, 2024 - nature.com
Gene drive elements promote the spread of linked traits and can be used to change the
composition or fate of wild populations. Cleave and Rescue (ClvR) drive elements sit at a …

Gene drive strategies of pest control in agricultural systems: Challenges and opportunities

M Legros, JM Marshall, S Macfadyen… - Evolutionary …, 2021 - Wiley Online Library
Recent advances in gene‐editing technologies have opened new avenues for genetic pest
control strategies, in particular around the use of gene drives to suppress or modify pest …

High-resolution in situ analysis of Cas9 germline transcript distributions in gene-drive Anopheles mosquitoes

G Terradas, A Hermann, AA James, W McGinnis, E Bier - G3, 2022 - academic.oup.com
Gene drives are programmable genetic elements that can spread beneficial traits into wild
populations to aid in vector-borne pathogen control. Two different drives have been …