The choice of biomaterials available for regenerative medicine continues to grow rapidly,
with new materials often claiming advantages over the short-comings of those already in …

Overview IL-7 is a member of the family of cytokines with four anti-parallel α helixes that bind
Type I cytokine receptors. It is produced by stromal cells and is required for development …

A growth factor for vascular endothelial cells was identified in the media conditioned by
bovine pituitary follicular cells and purified to homogeneity by a combination of ammonium …

As we enter the new millennium, the prospects for the field of Biomedical Engineering are
bright. Individuals interested in pursuing careers in this field continue to increase and the …

The proteoglycan superfamily now contains more than 30 full-time molecules that fulfill a
variety of biological functions. Proteoglycans act as tissue organizers, influence cell growth …

Murine IgM monoclonal antibody STRO-1 identifies a cell surface antigen expressed by
stromal elements in human bone marrow (BM). STRO-1 binds to approximately 10% of BM …

Bioscaffolds derived from xenogeneic extracellular matrix (ECM) have been used in
numerous tissue engineering applications. The safety and efficacy of such scaffolds when …

The extracellular matrix (ECM) consists of a complex mixture of structural and functional
proteins and serves an important role in tissue and organ morphogenesis, maintenance of …

When tissue loss disrupts normal architecture in higher vertebrate adult animals, the organ
fails to regenerate. Instead, repair proceeds as a fibroproliferative response that develops …

We have analysed the interactions of three proteoglycans of the decorin family, decorin,
biglycan and fibromodulin, with transforming growth factor beta (TGF-beta). The …