Weaning stress and gastrointestinal barrier development: Implications for lifelong gut health in pigs

AJ Moeser, CS Pohl, M Rajput - Animal Nutrition, 2017 - Elsevier
The gastrointestinal (GI) barrier serves a critical role in survival and overall health of animals
and humans. Several layers of barrier defense mechanisms are provided by the epithelial …

Nutritional regulation of gut barrier integrity in weaning piglets

SC Modina, U Polito, R Rossi, C Corino… - Animals, 2019 - mdpi.com
Simple Summary Weaning is a very stressful period in the piglet's life in intensive farming: it
is a sudden process occurring between three to four weeks of age, when the gastrointestinal …

The cholinergic system and inflammation: common pathways in delirium pathophysiology

J Cerejeira, V Nogueira, P Luís… - Journal of the …, 2012 - Wiley Online Library
Objectives To investigate whether delirium is associated with an unbalanced inflammatory
response or a dysfunctional interaction between the cholinergic and immune systems …

Inhibition of tyrosine-phosphorylated STAT3 in human breast and lung cancer cells by manuka honey is mediated by selective antagonism of the IL-6 receptor

P Aryappalli, K Shabbiri, RJ Masad… - International journal of …, 2019 - mdpi.com
Aberrantly high levels of tyrosine-phosphorylated signal transducer and activator of
transcription 3 (p-STAT3) are found constitutively in~ 50% of human lung and breast …

The M3 muscarinic receptor is required for optimal adaptive immunity to helminth and bacterial infection

M Darby, C Schnoeller, A Vira, F Culley, S Bobat… - PLoS …, 2015 - journals.plos.org
Innate immunity is regulated by cholinergic signalling through nicotinic acetylcholine
receptors. We show here that signalling through the M3 muscarinic acetylcholine receptor …

Neuroimmune regulation of lung infection and inflammation

Y Huang, C Zhao, X Su - QJM: An International Journal of …, 2019 - academic.oup.com
The distal airway of the lung is innervated by vagus nerve. Upon stimulation, vagus nerve
endings release acetylcholine or neuropeptides via C-fiber afferents to regulate lung …

Signals of vagal circuits engaging with AKT1 in α7 nAChR+ CD11b+ cells lessen E. coli and LPS-induced acute inflammatory injury

C Zhao, X Yang, EM Su, Y Huang, L Li, MA Matthay… - Cell discovery, 2017 - nature.com
Vagal circuits-α7 nAChR (α7 nicotinic acetylcholine receptor, coded by Chrna7) signaling
utilizes spleen as a hub to dampen systemic inflammatory responses. Vagal innervations …

Exosomes from bacteria (Streptococcus parauberis) challenged olive flounder (Paralichthys olivaceus): Isolation, molecular characterization, wound healing, and …

EHTT Jayathilaka, SL Edirisinghe, C Oh… - Fish & Shellfish …, 2023 - Elsevier
Exosomes are a group of extracellular vesicles carrying membrane proteins, lipids, RNAs,
and, cytosolic proteins, which play key role in intercellular communication and homeostasis …

Bioactive properties and untargeted metabolomics analysis of bioaccessible fractions of non-fermented and fermented date fruit pomace by novel yeast isolates

M Ayyash, M Tarique, M Alaryani, A Al-Sbiei, R Masad… - Food Chemistry, 2022 - Elsevier
In this study, attempts were made to utilize date by-product (date fruit pomace; DFP). This
study aimed to investigate the health-promoting benefits of the fermented and non …

Caffeine intake may modulate inflammation markers in trained rats

RP Barcelos, MA Souza, GP Amaral, ST Stefanello… - Nutrients, 2014 - mdpi.com
Caffeine is presented in many commercial products and has been proven to induce
ergogenic effects in exercise, mainly related to redox status homeostasis, inflammation and …