Neuroinflammation following traumatic brain injury: take it seriously or not
R Zheng, K Lee, Z Qi, Z Wang, Z Xu, X Wu… - Frontiers in …, 2022 - frontiersin.org
Traumatic brain injury (TBI) is associated with high mortality and disability, with a substantial
socioeconomic burden. With the standardization of the treatment process, there is increasing …
socioeconomic burden. With the standardization of the treatment process, there is increasing …
Identifying the phenotypes of diffuse axonal injury following traumatic brain injury
Diffuse axonal injury (DAI) is a significant feature of traumatic brain injury (TBI) across all
injury severities and is driven by the primary mechanical insult and secondary biochemical …
injury severities and is driven by the primary mechanical insult and secondary biochemical …
Diffusion tensor imaging and plasma immunological biomarker panel in a rat traumatic brain injury (TBI) model and in human clinical TBI
XV To, AZ Mohamed, P Cumming… - Frontiers in …, 2024 - frontiersin.org
Introduction Neuroinflammatory reactions play a significant role in the pathology and long-
term consequences of traumatic brain injury (TBI) and may mediate salutogenic processes …
term consequences of traumatic brain injury (TBI) and may mediate salutogenic processes …
[HTML][HTML] Evaluating the effect of post-traumatic hypoxia on the development of axonal injury following traumatic brain injury in sheep
JM Sharkey, RD Quarrington, JL Krieg, L Kaukas… - Brain Research, 2023 - Elsevier
Damage to the axonal white matter tracts within the brain is a key cause of neurological
impairment and long-term disability following traumatic brain injury (TBI). Understanding …
impairment and long-term disability following traumatic brain injury (TBI). Understanding …
Traumatic brain injury augurs ill for prolonged deficits in the brain's structural and functional integrity following controlled cortical impact injury
Previous neuroimaging studies in rodents investigated effects of the controlled cortical
impact (CCI) model of traumatic brain injury (TBI) within one-month post-TBI. This study …
impact (CCI) model of traumatic brain injury (TBI) within one-month post-TBI. This study …
Characterization of traumatic brain injury in a gyrencephalic ferret model using the novel closed head injury model of engineered rotational acceleration (CHIMERA)
Traumatic brain injury (TBI) results from mechanical force to the brain and leads to a series
of biochemical responses that further damage neurons and supporting cells. Clinically, most …
of biochemical responses that further damage neurons and supporting cells. Clinically, most …
Evolving brain and behaviour changes in rats following repetitive subconcussive head impacts
WS Hoogenboom, TG Rubin, K Ambadipudi… - Brain …, 2023 - academic.oup.com
There is growing concern that repetitive subconcussive head impacts, independent of
concussion, alter brain structure and function, and may disproportionately affect the …
concussion, alter brain structure and function, and may disproportionately affect the …
CORM-3 ameliorates neurodegeneration in the amygdala and improves depression-and anxiety-like behavior in a rat model of combined traumatic brain injury and …
Y Li, LM Zhang, DX Zhang, WC Zheng, Y Bai… - Neurochemistry …, 2020 - Elsevier
Objective Emotional disturbances characterized by depression and anxiety among survivors
of traumatic brain injury (TBI) impact the quality of life severely. Currently, there is a lack of …
of traumatic brain injury (TBI) impact the quality of life severely. Currently, there is a lack of …
Finding the spatial co-variation of brain deformation with principal component analysis
Objective: Strain and strain rate are effective traumatic brain injury metrics. In finite element
(FE) head model, thousands of elements were used to represent the spatial distribution of …
(FE) head model, thousands of elements were used to represent the spatial distribution of …
Initial Severity of Injury Has Little Effect on the Temporal Profile of Long-Term Deficits in Locomotion, Anxiety, and Cognitive Function After Diffuse Traumatic Brain …
Traumatic brain injury (TBI) is associated with persistent impairments in multiple domains,
including cognitive and neuropsychiatric function. Previous literature has suggested that the …
including cognitive and neuropsychiatric function. Previous literature has suggested that the …