Macrophages: Their role, activation and polarization in pulmonary diseases
Macrophages, circulating in the blood or concatenated into different organs and tissues
constitute the first barrier against any disease. They are foremost controllers of both innate …
constitute the first barrier against any disease. They are foremost controllers of both innate …
Macrophage: a cell with many faces and functions in tuberculosis
Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which
primarily infects the macrophages. Nearly a quarter of the world's population is infected …
primarily infects the macrophages. Nearly a quarter of the world's population is infected …
Role of apoptosis and autophagy in tuberculosis
A Lam, R Prabhu, CM Gross… - … of Physiology-Lung …, 2017 - journals.physiology.org
Tuberculosis (TB) is one of the oldest known human diseases and is transmitted by the
bacteria Mycobacterium tuberculosis (Mtb). TB has a rich history with evidence of TB …
bacteria Mycobacterium tuberculosis (Mtb). TB has a rich history with evidence of TB …
Natural and trained innate immunity against Mycobacterium tuberculosis
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) infection, remains a major
global health emergency. It is estimated that one third of global population are affected …
global health emergency. It is estimated that one third of global population are affected …
Hacking the host: exploitation of macrophage polarization by intracellular bacterial pathogens
JD Thiriot, YB Martinez-Martinez… - Pathogens and …, 2020 - academic.oup.com
Macrophages play an integral role in host defenses against intracellular bacterial
pathogens. A remarkable plasticity allows for adaptation to the needs of the host to …
pathogens. A remarkable plasticity allows for adaptation to the needs of the host to …
The Role of microRNAs and Long Non-Coding RNAs in the Regulation of the Immune Response to Mycobacterium tuberculosis Infection
M Kundu, J Basu - Frontiers in immunology, 2021 - frontiersin.org
Non-coding RNAs have emerged as critical regulators of the immune response to infection.
MicroRNAs (miRNAs) are small non-coding RNAs which regulate host defense mechanisms …
MicroRNAs (miRNAs) are small non-coding RNAs which regulate host defense mechanisms …
Reinventing the human tuberculosis (TB) granuloma: Learning from the cancer field
S Ashenafi, S Brighenti - Frontiers in Immunology, 2022 - frontiersin.org
Tuberculosis (TB) remains one of the deadliest infectious diseases in the world and every 20
seconds a person dies from TB. An important attribute of human TB is induction of a …
seconds a person dies from TB. An important attribute of human TB is induction of a …
STAT1 and its related molecules as potential biomarkers in Mycobacterium tuberculosis infection
X Yi, B Zhang, Y Fu, Z Yi - Journal of Cellular and Molecular …, 2020 - Wiley Online Library
Tuberculosis (TB) is a severe infectious disease that seriously endangers human health.
The immune defence mechanism of the body against TB is still unclear. The purpose of this …
The immune defence mechanism of the body against TB is still unclear. The purpose of this …
Preventing acute lung injury from progressing to pulmonary fibrosis by maintaining ERS homeostasis through a multistage targeting nanomicelle
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) or pulmonary fibrosis (PF)
has been regarded as a global health issue with high mortality and limited drug therapy …
has been regarded as a global health issue with high mortality and limited drug therapy …
BAG2 ameliorates endoplasmic reticulum stress-induced cell apoptosis in Mycobacterium tuberculosis-infected macrophages through selective autophagy
S Liang, F Wang, C Bao, J Han, Y Guo, F Liu, Y Zhang - Autophagy, 2020 - Taylor & Francis
ABSTRACT BAG2 (BCL2 associated athanogene 2) is associated with cell fate
determination in response to various pathological conditions. However, the effects of BAG2 …
determination in response to various pathological conditions. However, the effects of BAG2 …