Exercise after spinal cord injury as an agent for neuroprotection, regeneration and rehabilitation

HR Sandrow-Feinberg, JD Houlé - Brain research, 2015 - Elsevier
Spinal cord injury (SCI) is a traumatic event from which there is limited recovery of function,
despite the best efforts of many investigators to devise realistic therapeutic treatments. Partly …

Rehabilitation following spinal cord injury: how animal models can help our understanding of exercise-induced neuroplasticity

K Loy, FM Bareyre - Neural regeneration research, 2019 - journals.lww.com
Spinal cord injury is a devastating condition that is followed by long and often unsuccessful
recovery after trauma. The state of the art approach to manage paralysis and concomitant …

Exercise modulates chloride homeostasis after spinal cord injury

MP Côté, S Gandhi, M Zambrotta… - Journal of …, 2014 - Soc Neuroscience
Activity-based therapies are routinely integrated in spinal cord injury (SCI) rehabilitation
programs because they result in a reduction of hyperreflexia and spasticity. However, the …

Electrical stimulation and motor recovery

W Young - Cell transplantation, 2015 - journals.sagepub.com
In recent years, several investigators have successfully regenerated axons in animal spinal
cords without locomotor recovery. One explanation is that the animals were not trained to …

Traumatic Human Spinal Cord Injury: Are Single Treatments Enough to Solve the Problem?

I Grijalva-Otero, E Doncel-Pérez - Archives of Medical Research, 2024 - Elsevier
Traumatic spinal cord injury (SCI) results in partial or complete motor deficits, such as
paraplegia, tetraplegia, and sphincter control, as well as sensory disturbances and …

Delayed intervention with intermittent hypoxia and task training improves forelimb function in a rat model of cervical spinal injury

EJ Prosser-Loose, A Hassan, GS Mitchell… - Journal of …, 2015 - liebertpub.com
The reduction of motor, sensory and autonomic function below the level of an incomplete
spinal cord injury (SCI) has devastating consequences. One approach to restore function is …

Activity-based physical rehabilitation with adjuvant testosterone to promote neuromuscular recovery after spinal cord injury

DM Otzel, J Lee, F Ye, SE Borst, JF Yarrow - International Journal of …, 2018 - mdpi.com
Neuromuscular impairment and reduced musculoskeletal integrity are hallmarks of spinal
cord injury (SCI) that hinder locomotor recovery. These impairments are precipitated by the …

Stem cell conditioned medium treatment for canine spinal cord injury: pilot feasibility study

Z Vikartovska, M Kuricova, J Farbakova… - International journal of …, 2020 - mdpi.com
Spinal cord injury (SCI) involves nerve damage and often leads to motor, sensory and
autonomic dysfunctions. In the present study, we have designed a clinical protocol to assess …

Reaching and grasping training improves functional recovery after chronic cervical spinal cord injury

C Gallegos, M Carey, Y Zheng, X He… - Frontiers in Cellular …, 2020 - frontiersin.org
Previous studies suggest locomotion training could be an effective non-invasive therapy
after spinal cord injury (SCI) using primarily acute thoracic injuries. However, the majority of …

[HTML][HTML] Effect of acute physical interventions on pathophysiology and recovery after spinal cord injury: a comprehensive review of the literature

NE Lewis, TQ Tabarestani, BR Cellini, N Zhang… - Neurospine, 2022 - ncbi.nlm.nih.gov
Physical rehabilitation is essential for enhancing recovery in individuals with spinal cord
injury (SCI); however, aside from early surgical intervention and hemodynamic …